Radionuclide therapy requires patient-specific planning of the absorbed dose to target volumes, in most cases tumours, in order to achieve an expected biological effect, taking into account that the absorbed doses to normal organs and tissues should be kept as low as reasonably achievable. Therefore, the calculation of absorbed doses has to be as accurate as possible. The accuracy depends on th...

background: in radiation therapy, water is the phantom material of choice, both for reference and for relative dosimetry measurements. solid phantoms, however, are more useful for routine measurements because they tend to be more robust and easier to set up than water phantoms. materials and methods: fluka input data cards have been arranged in sequential order. a simple cylindrical geometry wi...

background: palladium-103 (103pd) is a brachytherapy source for cancer treatment. the monte carlo codes are usually applied for dose distribution and effect of shieldings. monte carlo calculation of dose distribution in water phantom due to a med3633 103pd source is presented in this work. materials and methods: the dose distribution around the 103pd model med3633 located in the center of 30×30...

background: electronic portal imaging devices (epids) play an important role in radiation therapy portal imaging, geometric and dosimetric verifications. a successful utilization of epids for imaging and dosimetric purposes requires a reliable quality control process routine to be carried out regularly. in this study, two in-house phantoms were developed and analyzed for implementation in a qua...

PURPOSE The aim of this work is to evaluate the application of tissue-specific dose kernels instead of water dose kernels to improve the accuracy of patient-specific dosimetry by taking tissue heterogeneities into consideration. MATERIALS AND METHODS Tissue-specific dose point kernels (DPKs) and dose voxel kernels (DVKs) for yttrium-90 (90Y), lutetium-177 (177Lu), and phosphorus-32 (32P) are ...

PURPOSE To find the optimal slice thickness (Δτ) setting for patient registration with kilovoltage cone-beam CT (kVCBCT) on the Varian On Board Imager (OBI) system by investigating the relationship of slice thickness to automatic registration accuracy and contrast-to-noise ratio. MATERIALS AND METHOD Automatic registration was performed on kVCBCT studies of the head and pelvis of a RANDO anth...

Introduction: Electronic portal imaging devices (EPIDs) could be used to dose verification of radiotherapy treatment plans. In vivo dose verification is performed to reduce differences found between dose delivered to the patient and the prescribed dose. The aim of this study was to perform a fast and efficient technique for the verification of delivered dose to the patient usin...

BACKGROUND Radiation-therapy is a complex process with multiple steps, each of which has an impact on the quality of treatment. Accurate dosimetry is a critical step during the radiotherapy of cancer patients.The aim of the present study was to measure and evaluate the doses of two cobalt- 60 (60Co) teletherapy units GWXJ80 of NPIC China and Theratron 780 of AECL Canada at various points within...

Diagonal diffusion-weighted imaging (dDWI) uses simultaneous maximized application of 3 orthogonal gradient systems as opposed to sequential acquisition in 3 directions in conventional 3-scan trace DWI (tDWI). Several theoretical advantages of dDWI vs. tDWI include reduced artifacts and increased sharpness. We compared apparent diffusion coefficient (ADC) quantification and image quality betwee...

In order to establish an organ and effective dose database for Iranian children undergoing computed tomography (CT) examinations, in the first step, two Iranian 11-year-old phantoms were constructed from image series obtained from CT and magnetic resonance imaging (MRI). Organ and effective doses for these phantoms were calculated for head, chest, abdomen-pelvis and chest-abdomen-pelvis (CAP) s...