many recent studies have shown that glycosylation patterns of agaricus bisporus are similar to those of mammalians, so that this organism is a good candidate for the expression of glycosylated pharmaceutical protein. to achieve constant interested gene expression in all cells of the organism, proper promoter isolation is necessary. to isolate this promoter, pcr with specific primers was perform...

background: to study the pattern of acute chemical and pharmaceutical poisoning in ahmadabad, gujarat, india. methods: this was a prospective study of patients with chemical and pharmaceutical poisoning who were admitted to the emergency department of civil hospital ahmadabad, from 1st october 2006 to 30th september 2007. socio-demographic details, intention of poisoning, type of poison, durati...

Each year, the American Academy of Neurology (AAN)’s A.B. Baker Section on Neurologic Education conducts an Education Colloquium at the AAN annual meeting. The goals of the Colloquium are to heighten awareness, stimulate creative approaches, and foster dialogue among members regarding current trends, challenges, and opportunities in neurologic education. The theme of the 2004 Education Colloqui...

BACKGROUND Many academic medical centers have increased their use of advertising to attract patients. While the content of direct-to-consumer pharmaceutical advertisements (ads) has been studied, to our knowledge, advertising by academic medical centers has not. We aimed to characterize advertising by the nation's top academic medical centers. METHODS We contacted all 17 medical centers named...

BACKGROUND In view of rapidly increasing prescription costs, case-mix adjustment should be considered for effective control of costs. We have estimated the variability in pharmacy costs explained by ACG in centers using patient electronic records, profiled centers and physicians and analyzed the correlation between cost and quality of prescription. METHODS We analyzed 65,630 patient records a...

Sharon L. Walsh, PhD Center on Drug and Alcohol Research Departments of Behavioral Science, Psychiatry, Pharmacology, and Pharmaceutical Sciences Lexington, KY 40508, USA Email: [email protected] D espite this common warning found in virtually all opioid product package inserts, reports on prescribing practices suggest that all too often this warning is ignored—with grave consequences. Not o...

I read with interest Mr. Aicher’s editorial in the Aesthetic Surgery Journal, and wanted to echo and share some of my thoughts and concerns on this new government mandate. Approximately 2 years ago the Centers for Medicare & Medicaid Services (CMS) was tasked by the federal government to oversee and report all payments made to health care providers, owing to concerns that payments from the phar...

In 2007 the Association of Research-Based Pharmaceutical Companies (vfa) published recommendations to improve the quality and transparency of non-interventional studies. These recommendations include quality assurance measures, in particular with respect to transparency as well as for the verification of the data collected in these studies. This publication presents the results of a survey on f...

The structures of complex polyketide natural products, such as erythromycin, are programmed by multifunctional polyketide synthases (PKSs) that contain modular arrangements of functional domains. The colinearity between the activities of modular PKS domains and structure of the polyketide product portends the generation of novel organic compounds-"unnatural" natural products-by genetic manipula...