Ceftriaxone (CFTX) sodium is a third-generation, broad-spectrum cephalosporin that is resistant to betalactamases. An alternative bioassay for the assessment of the potency of this drug in pharmaceutical formulations has not been previously reported. Thus, this paper reports the development and full validation of a 3 x 3 agar diffusion bioassay using a cylinder-plate method to quantify CFTX sod...

The objective of present study was to develop and validate a dissolution test for polyherbal hepatoprotective tablets containing andrographolide with bio-relevant media. Different dissolution conditions such as basket (type I)/paddle (type II) agitation, rotation speed, dissolution medium and volume were evaluated. The dissolution samples were analyzed and validated using a high-performance liq...

Received (received date) Revised (revised date) Communicated by Christian Lengauer ABSTRACT Programming with parallel skeletons is an attractive framework because it encourages programmers to develop eecient and portable parallel programs. However, extracting parallelism from sequential speciications and constructing eecient parallel programs using the skeletons are still diicult tasks. In this...

The blind separation of multiple co-channel binary digital signals using an antenna array involves finding a factorization of a data matrix X into X AS, where all entries of S are 1 or −1. It is shown that this problem can be solved exactly and non-iteratively, via a certain generalized eigenvalue decomposition. As indicated by simulations, the algorithm is robust in the presence of noise. An i...

In this paper we present a Quantified SWOT (Strengths, Weaknesses, Opportunities and Threats) analytical method which provides more detailed and quantified data for SWOT analysis. The Quantified SWOT analytical method adopts the concept of Multiple-Attribute Decision Making (MADM), which uses a multi-layer scheme to simplify complicated problems, and thus is able to perform SWOT analysis on sev...

The development of sound Analytical method(s) is of supreme importance during the process of drug discovery, release to market and development, culminating in a marketing approval. The objective of this paper is to review the method development, optimize and validation of the method for the drug product from the developmental stage of the formulation to commercial batch of the product. Method d...

AbstractSubstandard and falsified antimalarial and antibiotic medicines represent a serious problem for public health, especially in low- and middle-income countries. However, information on the prevalence of poor-quality medicines is limited. In the present study, samples of six antimalarial and six antibiotic medicines were collected from 31 health facilities and drug outlets in southern Mala...

abstract: a time domain semi-analytical solution to study thermoelastic creep behavior of  functionally graded rotating axisymmetric disks with variable thickness is presented. the rate type governing differential equations for the considered structure are derived and analytically solved. to solve these  equations, the disk is divided into some virtual sub-domains. general solution of  equilibr...