This study was performed to obtain a comprehensive overview of the benefits and risks of second-line irinotecan monotherapy for advanced colorectal cancer. The literature was systematically reviewed to identify phase II and phase III trials that investigated the effect of second-line monotherapy with irinotecan. Thirty studies were included in this review: 25 phase II studies including 32 sampl...

Introduction Allergic rhinitis, like other allergic diseases, is one of the most common disorders during childhood; this study was conducted to assess and compare the prevalence and severity of allergic rhinitis in children and adolescents living in Kurdistan province. The study was aimed to provide a ground for the identification of likely causes and risk factors of this disorder. Materials an...

The aim of the present study was to provide a current survey of the species of parasites found in the Upper Paraná River floodplain, as well as to investigate which strategies and mechanisms used by parasites, are favored and which environmental factors influence the parasite community in the studied environments. During a seven-year period from February 2000 to September 2007, 3,768 fish belon...

Teamwork is becoming increasingly important in a large number of multiagent applications. With the growing importance of teamwork, there is now an increasing need for tools for analysis and evaluation of such teams. We are developing automated techniques for analyzing agent teams. In this paper we present ISAAC, an automated assistant that uses these techniques to perform post-hoc analysis of R...

This paper presents a description of ISAAC, the Immersive Simulation Animation And Construction program designed and built at the University of North Carolina at Chapel Hill (UNC-CH). ISAAC is a scene composition application for the interactive construction of virtual worlds. Working directly in a virtual environment, objects can be positioned, oriented and scaled using direct and indirect mani...

in all societies, considering the nature of physicians’ profession, regarded as one of the confident groups among other social strata as well as in the courts, physicians had very high dignity and acquired kings’ revere accordingly. however, in diplomatic relations confidence strengthens mutualties. isaac beg was one of iranian medics who arrived in the palace of stephan iii in 1474. in the afo...

The aim of this study wos to assess asthma prevalence in children between I3-14 years of age in East Jakarta. This study is a cross sectional-study which surveyed 2234 high school students betvveen the ages of I3 and l4 years in East Jakarta in 2001 using the ISAAC questionnaire. Bron'chial chatleige test was appLied holine substance to 186 sludents. Reports.based on the IsAACquestionnaire indi...