effects of different levels of dietary nucleotides (nt) were studied on muscle amino acid profile of rain bow trout with an average weight 11.35±0.32 over 8 weeks. this experimental was carried out in 700 l circular tanks with 40 fish per tank. nt was added to the diet at the rates of 0.0, 0.05, 0.1, 0.15 and 0.2%. fish were fed 5 times a day at a rate of 3-5% body weight. after 8 weeks of feed...

RPC-5 chromatography was used to examine the phenylalanyl transfer RNA (Phe-tRNA) of 25 normal rat and mouse tissues including adult, fetal, and regenerating liver; whole embryos; and other adult organs. Only a single major isoaccepting Phe-tRNA was found in every case. Phe-tRNA's from 25 transplantable rat tumors and 33 transplantable mouse tumors were similarly examined. Seventeen rat tumors ...

The tryptic peptides from human pepsin and gastricsin were purified and their sequences were determined. The sequence of 27 residues at the COOH-terminal end of human pepsin was found to be: -Ile-Leu-Gly-Asp-Val-Phe-Ile-ArgGln-Phe-Tyr-Thr-Val-Phe-Asp-Arg-Ala-Asn-Asn-GlnVal-Gly-Leu-Ala-Pro-Val-Ala. The sequence of 19 residues at the COOH-terminal end of human gastricsin was found to be: -Gln-Phe...

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z-Phe-Ala. It was lower on Z-Phe-Phe, Z-Glu-Tyr, Z-Glu-Phe, Z-Gly-Phe, and the lowest activity was on Z-Gly-Ala. We concl...

This systematic review and meta-analysis (MA) investigates the impact of elevated blood phenylalanine (Phe) on neuropsychiatric symptoms in adults with phenylketonuria (PKU). The meta-analysis of PKU is challenging because high-quality evidence is lacking due to the limited number of affected individuals and few placebo-controlled, double-blind studies of adults with high and low blood Phe. Neu...

Addition of the synthetic chemotactic factor, formyl-methionyl-leucyl-phenylala-nine (F-Met-Leu-Phe) to medium containing magnesium, sodium, and potassium results in a doubling of the "Na+, K+"-ATPase activity of the plasma membrane fraction from polymophonuclear leukocytes (PMN). This activation is sensitive to ouabain inhibition and is dose dependent, maximal activity occuring at 10(-9)MF-Met...

The effects of noradrenaline (Nor) and phenylephrine (Phe) on the isolated, non-precontracted perforating branch of the human internal mammary artery (HIMA) were investigated. Nor and Phe induced concentration-dependent contractions of intact and endothelium-denuded arterial rings with no statistically significant differences between the pEC(30) and maximal response values. The pretreatment of ...

The Phe-Q machine learning technique, a modified Q-learning technique, was developed to enable co-operating agents to communicate in learning to solve a problem. The Phe-Q learning technique combines Q-learning with synthetic pheromone to improve on the speed of convergence. The Phe-Q update equation includes a belief factor that reflects the confidence the agent has in the pheromone (the commu...