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Maneb (MB) is a manganese-containing ethylene bis-dithiocarbamate fungicide that is implicated as an environmental risk factor for Parkinson's disease, especially in combination with paraquat (PQ). Dithiocarbamates inhibit aldehyde dehydrogenases, but the relationship of this to the combined toxicity of MB + PQ is unclear because PQ is an oxidant and MB activates Nrf2 and increases cellular GSH...

Standard practice for grape disease management in Marlborough 10 years ago was to spray for diseases using calendar based spray programmes. Communication of grape disease management research has led to a change of practice for many grape growers. The key tool developed by the research programme was targeted spraying for diseases. This involved field monitoring for diseases and the use of decisi...

The fungicides used to control diseases in cereal production can have adverse effects on non-target fungi, with possible consequences for plant health and productivity. This study examined fungicide effects on fungal communities on winter wheat leaves in two areas of Sweden. High-throughput 454 sequencing of the fungal ITS2 region yielded 235 operational taxonomic units (OTUs) at the species le...

The gross and microscopic pathomorphological changes in internal organs were investigated for evaluation of the toxic effect of the triazole fungicide triticonazole. One control and three experimental groups of pigs, treated orally via a gastic tube at doses of 0.2 g/kg (group I), 1 g/kg (group II) and 2 g/kg (group III) (0.1LD50, 0.5LD50 and LD50 respectively) were used. The pigs were euthaniz...

Declines in bumblebee populations have led to investigations into potential causes - including agrochemical effects on bumblebee physiology. The indirect effects of agrochemicals (i.e. behavior modulation) have been postulated, but rarely directly tested. Olfactory information is critical in mediating bumblebee-floral interactions. As agrochemicals emit volatiles, they may indirectly modify for...