A plasticizer is a substance normally incorporated to a PVC resin or some other materials such as paints, to improve some of its properties as flexibility or processability. Phthalates, adipates, phosphates and some others are the main compounds used as plasticizers. Some of these compounds, as bis-(2-ethylhexyl) phthalate (DOP), are being questioned worldwide because of their potential toxicit...

BACKGROUND Emerging evidence suggests a potential role for ubiquitous environmental contaminants in the physiopathology of endometriosis. Di-(2-ethylhexyl)-phthalate (DEHP), the most commonly used plasticizer in flexible polyvinylchloride (PVC) formulations, is a widespread environmental contaminant with potentially adverse effects on fertility in animal models. In the present study, we tested ...

Phthalates are esters of phthalic acid and aliphatic alcohol added to plastic to improve its softness, flexibility, and extensibility. They easily migrate from plastic products into the environment because of their physical and chemical properties. This review summarises their characteristics, distribution in the environment, monitoring, use, toxic effects on human health, regulatory limits in ...

background: phthalate esters have been shown to cause reproductive toxicity in both developing and adult animals. objective: this study was designed to assess long-term effects of maternal exposure to di (2-ethylhexyl) phthalate (dehp) on reproductive ability of both neonatal and adult male offspring. materials and methods: 60 female rats randomly divided in four equal groups; vehicle control a...

Phthalates are organic contaminants that used as plasticizers in many plastic food packaging materials. Because of their lipophilic character, oils the primary source human exposure to phthalates. In this study, presence five phthalate esters; diethylhexyl (DEHP), dibutyl (DBP), butyl benzyl (BBP), diisononyl (DINP) and diisodecyl (DIDP) olive flavored with different materials marketed Turkey 2...

One of the most common environmentally relevant groups pollutants are phthalate esters. After decades industrial use, they have become ubiquitous in environment and analytical methods to chemically detect them trace amounts required. In this study, details Proton Transfer Reaction-Mass Spectrometry (PTR-MS) investigations for reactions phthalic acid ten esters with H3O+ as a function reduced el...

Growing concern that phthalic acid esters (PAE) may present a health hazard and possible deleterious effects on the ecological system has led to increased interest in the more subtle toxicity of those compounds. Although the acute toxicity of PAEs as a group is quite low, the intrinsic cellular toxicity increases with molecular weight. Whether the intrinsic toxicity is great enough to exert a s...

Numerous plastic devices and materials used for medical, dental, and food collection, processing, and packaging are made of poly(vinyl chloride) and plasticized mainly with di-2-ethylhexyl phthalate (DEHP) to impart the desired physical and chemical characteristics. Some finished products may contain more than 40% plasticizer, which may be leached from the material by blood (1) or milk (2) or v...