نتایج جستجو برای: phthalazine
تعداد نتایج: 192 فیلتر نتایج به سال:
ER~TONIN S (s-hydroxytryptamine) has only Bouckaert and Moraes (8) to reverse the vasorecently been isolated, synthesized and constrictor activity of defibrinated blood in available in quantities sufficient to study perfusion experiments; its action against pure its pharmacologic actions. In a brief span of serotonin is evaluated here; e) Pitressin tends time several publications have appeared ...
in this report, synthesis, characterization and application of silica perchloric acid nanosphere as a novel and heterogeneous catalyst is described. these nanospheres have been characterized by xrd, ft-ir, bet and tga spectra and also by sem and tem images. the results show that it has a spherical shape and the particles size are between 75 and 100 nm. the catalytic activity has been investigat...
Sulfonated magnetic nanoparticles (SO3H-Fe3O4@SiO2 MNPs) have been explored as an efficient, cost-effective, and recyclable nanocatalyst for the facile synthesis of 3,4-dihydro-2H-indazolo[1,2-b]phthalazin-1,6,11(13H)-triones through a one-pot three-component reaction between aldehydes, dimedone, and phthalhydrazide under mild and green (solvent-f...
3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4triazol-5-ylmethoxy)-pyrazolo[1,5-d][1,2,4]triazine (MRK-016) is a pyrazolotriazine with an affinity of between 0.8 and 1.5 nM for the benzodiazepine binding site of native rat brain and recombinant human 1-, 2-, 3-, and 5-containing GABAA receptors. It has inverse agonist efficacy selective for the 5 subtype, and this 5 inverse agonism...
Aldehyde oxidase-mediated oxidation of N-methylnicotinamide to N-methyl-2-pyridine-5-carboxamide (2-PY) and N-methyl-4pyridone-5-carboxamide (4-PY) in chimeric mice constructed by transplanting human hepatocytes into urokinase-type plasminogen activator-transgenic severe combined immunodeficient mice was examined in vivo and in vitro. The activity in liver cytosol of chimeric mice with a high r...
Aldehyde oxidase-mediated oxidation of N-methylnicotinamide to N-methyl-2-pyridine-5-carboxamide (2-PY) and N-methyl-4pyridone-5-carboxamide (4-PY) in chimeric mice constructed by transplanting human hepatocytes into urokinase-type plasminogen activator-transgenic severe combined immunodeficient mice was examined in vivo and in vitro. The activity in liver cytosol of chimeric mice with a high r...
Aldehyde oxidase-mediated oxidation of N-methylnicotinamide to N-methyl-2-pyridine-5-carboxamide (2-PY) and N-methyl-4pyridone-5-carboxamide (4-PY) in chimeric mice constructed by transplanting human hepatocytes into urokinase-type plasminogen activator-transgenic severe combined immunodeficient mice was examined in vivo and in vitro. The activity in liver cytosol of chimeric mice with a high r...
Aldehyde oxidase-mediated oxidation of N-methylnicotinamide to N-methyl-2-pyridine-5-carboxamide (2-PY) and N-methyl-4pyridone-5-carboxamide (4-PY) in chimeric mice constructed by transplanting human hepatocytes into urokinase-type plasminogen activator-transgenic severe combined immunodeficient mice was examined in vivo and in vitro. The activity in liver cytosol of chimeric mice with a high r...
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