Introduction: Phyllanthus niruri, Andrographis paniculata and Embilica officinalis are most important and high value medicinal plant known for its hepatoprotective activity. Several analytical methods including HPtlc and HPlc are reported for respective phytoconstituents. However, there is no simultaneous estimation of phyllanthin and gallic acid reported. the Objective of present work is to de...

Aspirin has been used for a long time as an analgesic and anti-pyretic drug. Limitations of its use, however, remain for the gastro-intestinal side effects and erosions. Although the role of aspirin on gastro-intestinal injury has been extensively studied, the molecular mechanisms underlying aspirin-induced liver and spleen pathophysiology are poorly defined. The present study has been conducte...

fects, such as methyl brevifolincarboxylate, from the leaves of Phyllanthus niruri, ebricoic acid from the extract of Phellinus givus, and forsythiaside from the fruit of Forsythia suspensa. In our attempts to search for compounds with vasorelaxant effects from various plants, in the present study we isolated three constituents from the heartwood of Acer nikoense (Aceraceae): A. nikoense is a J...

The antibacterial potency of alkaloid extracted from Phyllanthus niruri was examined on Fluoroquinolone resistant Escherichia coli isolated from different clinical samples using disk diffusion method. Different concentrations (0.1 – 5mg/ml) of the alkaloid were used. It was observed that at 0.5mg/ml the extract showed more potency on Escherichia coli isolated from urine than from other samples ...

Herpes simplex virus type 1 (HSV-1) infection has a prevalence of 70% in the human population. Treatment is based on acyclovir, valacyclovir, and foscarnet, three drugs that share the same mechanism of action and of which resistant strains have been isolated from patients. In this aspect, innovative drug therapies are required. Natural products offer unlimited opportunities for the discovery of...

Indonesians believe in a tradition passed from generation to about the properties of herbal medicine. Meniran leaf is one ber grown Asia and found many parts Indonesia. It contains flavonoids alkaloid able stimulate immune system antioxidants combat ROS. Antioxidant can neutralize effects caused by oxidative stress (a conndition where an imbbalance between oxidants body). Antioxidants prevent d...