نتایج جستجو برای: physician clinicians npcs

تعداد نتایج: 111701  

Journal: :Colloid and Interface Science Communications 2021

Polyphosphazene was synthesized by ultrasonic using 4,4-diaminodiphenyl ether and hexachlorocyclotriphosphazene (HCCP) as precursors. Next, it further carbonized functionalized to prepare the carboxylic-acid N, P co-doped carbon materials (NPCs-COOH). The structure of NPCs-COOH characterized FTIR, SEM XPS. sorption performance for U(VI) in solution were determined under diverse factors includin...

Journal: :Trends in cell biology 2003
Michael P Rout John D Aitchison Marcelo O Magnasco Brian T Chait

The eukaryotic nucleus is surrounded by a protective nuclear envelope, which is perforated by trafficking machines termed nuclear pore complexes (NPCs). The NPCs are the sole mediators of exchange between the nucleus and the cytoplasm. Small molecules pass through the NPCs unchallenged; however, large macromolecules are excluded unless chaperoned across by transport factors. Here, we suggest a ...

2010
Jan M. Allbeck

Certainly non-player characters (NPCs) can add richness to a game environment. A world without people (or at least humanoids) seems barren and artificial. People are often a major part of the setting of a game. Furthermore, watching NPCs perform and have a life outside of their interactions with the main character makes them appear more reasonable and believable. NPCs can also be used to move f...

Journal: :PLoS ONE 2008
Izuho Hatada Masakazu Namihira Sumiyo Morita Mika Kimura Takuro Horii Kinichi Nakashima

Epigenetic changes are thought to lead to alterations in the property of cells, such as differentiation potential. Neural precursor cells (NPCs) differentiate only into neurons in the midgestational brain, yet they become able to generate astrocytes in the late stage of development. This differentiation-potential switch could be explained by epigenetic changes, since the promoters of astrocyte-...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Soheila Karimi-Abdolrezaee Eftekhar Eftekharpour Jian Wang Desiree Schut Michael G Fehlings

The transplantation of neural stem/progenitor cells (NPCs) is a promising therapeutic strategy for spinal cord injury (SCI). However, to date NPC transplantation has exhibited only limited success in the treatment of chronic SCI. Here, we show that chondroitin sulfate proteoglycans (CSPGs) in the glial scar around the site of chronic SCI negatively influence the long-term survival and integrati...

Journal: :Journal of virology 2013
Xing Pan Xiao-Jun Li Xi-Juan Liu Hui Yuan Jia-Fu Li Ying-Liang Duan Han-Qing Ye Ya-Ru Fu Guan-Hua Qiao Cong-Cong Wu Bo Yang Xiao-Hui Tian Kang-Hong Hu Ling-Feng Miao Xiao-Ling Chen Jun Zheng Simon Rayner Philip H Schwartz William J Britt Jiang Xu Min-Hua Luo

Congenital human cytomegalovirus (HCMV) infection is the most frequent infectious cause of birth defects, primarily neurological disorders. Neural progenitor/stem cells (NPCs) are the major cell type in the subventricular zone and are susceptible to HCMV infection. In culture, the differentiation status of NPCs may change with passage, which in turn may alter susceptibility to virus infection. ...

2014
Eiichi Ninomiya Taeka Hattori Masashi Toyoda Akihiro Umezawa Takashi Hamazaki Haruo Shintaku

Glucocorticoids (GCs) are frequently used for treating and preventing chronic lung disease and circulatory dysfunction in premature infants. However, there is growing concern about the detrimental effects of systemic GC administration on neurodevelopment. The first choice of GCs to minimize the adverse effects on the developing brain is still under debate. We investigated the effect of commonly...

2017
Ping Liu Feng Chang Ting Zhang Gang Gao Chen Yu Sheng-Qiang Ding Gen-Le Zuo Xin-Hu Huang

Objectives To investigate the role of the microRNA-125a (miR-125a) and BAK1 in intervertebral disc degeneration (IDD). Materials and Methods Degenerative lumbar nucleus pulposus (NP) tissues were obtained from 193 patients who underwent resection, and normal controls consisted of normal NP tissues from 32 patients with traumatic lumbar fracture in our hospital. All patients were graded accord...

Journal: :Journal of cell science 2017
Jindřiška Fišerová Michaela Efenberková Tomáš Sieger Miloslava Maninová Jana Uhlířová Pavel Hozák

The nuclear periphery (NP) plays a substantial role in chromatin organization. Heterochromatin at the NP is interspersed with active chromatin surrounding nuclear pore complexes (NPCs); however, details of the peripheral chromatin organization are missing. To discern the distribution of epigenetic marks at the NP of HeLa nuclei, we used structured illumination microscopy combined with a new MAT...

2014
Qiang Liu Di Wu Na Ni Huixia Ren Chuanming Luo Chengwei He Jing-Xuan Kang Jian-Bo Wan Huanxing Su

The omega-3 polyunsaturated fatty acids (ω-3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), derived mainly from fish oil, play important roles in brain development and neuroplasticity. Here, we reported that application of ω-3 PUFAs significantly protected mouse neural progenitor cells (NPCs) against H2O2-induced oxidative injury. We also isolated NPCs from transgenic mice ...

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