By analyzing $e^+e^-$ annihilation data corresponding to an integrated luminosity of $2.93\,\rm fb^{-1}$ collected at the center-of-mass energy 3.773\,GeV with BESIII detector, we report first observations doubly Cabibbo-suppressed decays $D^+\to K^+\pi^0\pi^0$ and K^+\pi^0\eta$. The branching fractions K^+\pi^0\eta$ are measured be $(2.1 \pm 0.4_{\rm stat} 0.1_{\rm syst})\times 10^{-4}$ 0.5_{\...

Many studies have indicated that ozone is associated with morbidity and mortality. A few studies have reported that the association is heterogeneous across seasons and geographic regions. However, little information is available on whether both temperature and geographic factors simultaneously modify the ozone effect. This study used a Poisson regression model to explore whether temperature mod...

Schlüter, Klaus-Dieter, Andreas Simm, Matthias Schäfer, Gerhild Taimor, and Hans Michael Piper. Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1655–H1663, 1999.—The present study investigated the role of early response kinase (ERK) and phosphatidylinositol 3 (PI 3)-kinase in ventricular card...

The R6K gamma origin core contains the P2 promoter, whose -10 and -35 hexamers overlap two of the seven binding sites for the R6K-encoded pi protein. Two mutations, P2-201 and P2-203, which lie within the -35 region of P2, are shown to confer a promoter-down phenotype. We demonstrate here that these mutations prevent replication of a gamma origin core plasmid. To determine whether or not the re...

The role of phosphatidylinositol (PI) 3-kinase for insulin- and contraction-stimulated muscle glucose transport was investigated in rat skeletal muscle perfused with a cell-free perfusate. The insulin receptor substrate-1-associated PI 3-kinase activity was increased sixfold upon insulin stimulation but was unaffected by contractions. In addition, the insulin-stimulated PI 3-kinase activity and...

Motivated by the significant experimental progress in probing semileptonic decays $D\ensuremath{\rightarrow}{P}_{1}{P}_{2}{\ensuremath{\ell}}^{+}{\ensuremath{\nu}}_{\ensuremath{\ell}}$ $(\ensuremath{\ell}=\ensuremath{\mu},e)$, we analyze branching ratios of with nonresonant, light scalar meson resonant, and vector resonant contributions this work. We obtain hadronic amplitude relations between ...

Broomsedge (Andropogon virginicus L.) is a dominant grass revegetating many abandoned coal-mined lands in West Virginia, USA. Residual soils on such sites are often characterized by low pH, low nutrients, and high aluminium. Experiments were conducted to assess the resistance of broomsedge to limited phosphorus (Pi) availability and to investigate the role that arbuscular mycorrhizal (AM) fungi...

The growth of ‘Ridge Pineapple’ sweet orange [Citrus sinensis (L.) Osbeck] seedlings and their susceptibility to Phytophthora root rot were studied under contrasting supplies of phosphate (Pi) or Phosphite (Phi). After 10 weeks of repeated applications of nutrient solutions, Phi concentrations were barely detectable in soil. Soil Pi was higher in Phi treatments than in pots that received Pi alo...