Background: To examine whether embolization of dural or pial blood supply branch is more efficient for symptom alleviation for unruptured mixed dural-pial arteriovenous malformations (DPAVMs). Methods: We retrospectively reviewed 30 DPAVM patients from a database of 425 consecutive cerebral arteriovenous malformation (CAVM) patients who underwent endovascular embolization between January 2010 a...

conclusions alterations were present in both the aspect and spacing of collagen fibrils and in the shape of elastic fibers. the present familial combination of scad and edsh, with almost similar ultrastructural features suggests a possible connection between both conditions. case presentation we present a woman with scad and her five close relatives showing obvious or suggestive signs of edsh. ...

In patients with high-grade atherosclerotic stenosis or occlusion of the extracranial cerebral arteries, subarachnoid hemorrhage (SAH) may occur, potentially due to rupture of fragile dilated pial collateral vessels. This association has been well described in Moyamoya disease. There are only few cases in the literature that reported SAH due to bilateral carotid artery stenosis but intraventric...

Background: There is controversy regarding the need to use advanced imaging select candidates for thrombectomy in late window acute ischemic stroke (AIS). Hypoattenuation on CT angiography source images (CTA-SI) arterial phase has been shown be more sensitive than Alberta Stroke Program Early score (ASPECTS) of brain parenchyma determine tissue at risk ischemia. Our hypothesis that addition a s...

Vascular calcification is the abnormal deposition of calcium phosphate complexes in blood vessels, which regarded as pathological basis multiple cardiovascular diseases. The flowing exerts a frictional force called shear stress on vascular wall. Blood vessels have different hydrodynamic properties due to discrepancies geometric and mechanical properties. disturbance flow bending area branch poi...

Many brain tumors are highly resistant to chemotherapy, presumably due to the presence of a tight blood-tumor barrier. For a better understanding of the regulation of this barrier by the brain environment, a new intravital microscopy model was established by transplanting tumor tissue into cranial windows in both rats and mice. The model was characterized by RBC velocities, vessel diameters, an...

It has been proposed that sympathetic activation may prevent maximum dilatation of extra-parenchymal cerebral vessels during hemorrhagic hypotension and hypercapnia. In the present study, the effect of alpha-adrenoreceptor antagonists (phenoxybenzamine 1.5 mg kg-1 or phentolamine 8 mg kg-1) on pial vessel diameter was studied in the cat during hypotension and hypercapnia alone or in combination...