The severity of inflammation in sympathetic ophthalmia is related to the degree of pigmentation, and the granulomatous response seems to be related to pigmentation. Eosinophilia is also associated with pigmentation, but this association appears to be fortuitous and is a result of the association of eosinophilia with severity of the inflammation.

Trade-offs in resource allocation have been widely stated as the means by which the honesty of ornamental traits is maintained, but an alternative to this resource trade-off hypothesis is that production of ornamentation is linked to the biochemical efficiency of vital cellular processes. Carotenoids are antioxidants, potentially tying carotenoid-based coloration to the oxidative state of an or...

Cellular homeostasis is an outcome of complex interacting processes with nonlinear feedbacks that can span distinct spatial and temporal dimensions. Skin tanning is one such dynamic response that maintains genome integrity of epidermal cells. Although pathways underlying hyperpigmentation cascade are recognized, negative feedback regulatory loops that can dampen the activated melanogenesis proc...

Epidermolysis bullosa simplex with mottled hyperpigmentation (EBS-MP) is an uncommon subtype of EBS. Its clinical features depend on the age of diagnosis, and clinical variations have been described even within family members. We present six cases from two unrelated Spanish families each with several affected members with EBS-MP and review the clinical and genetic findings in all reported patie...

this study was conducted to examine morphometric and meristic characteristics alongside pigmentation patterns of bream larvae, abramis brama orientalis, in four stages of larval development. morphological characters including total length (tl), standard length (sl), notochord length (nl), head length (hl), head depth (hd), eye diameter (ed) and mouth width (mw) were examined from hatching time ...

Near-infrared fluorescence imaging (NIRFI) and far-red fluorescence imaging (FRFI) were used to investigate effects of depilation-induced skin pigmentation and diet-induced background fluorescence on fluorescent signal amplitude and lymphatic contraction frequency in C57BL6 mice. Far-red fluorescent signal amplitude, but not frequency, was affected by diet-induced fluorescence, which was remove...

Rates of skin cancer continue to increase despite the improved use of traditional sunscreens to minimize damage from ultraviolet radiation. The public perception of tanned skin as being healthy and desirable, combined with the rising demand for treatments to repair irregular skin pigmentation and the desire to increase or decrease constitutive skin pigmentation, arouses great interest pharmaceu...

BACKGROUND AND AIM: Oral pigmentation is a condition in which the color of oral mucosa such as gingival mucosa changes. Some exogenous and endogenous factors may lead to oral pigmentation. Secondhand smoke (SHS) or environmental tobacco smoke (ETS) is indirect smoking of an active smoker’s exhalation that can lead to cardiovascular, respiratory system, and some...

PURPOSE To find CT and MR characteristics of normal leptomeningeal melanin, which can be macroscopically visible at autopsy in decedents with deeply pigmented skin. METHODS For the normal anatomic study, there were two black subjects who had brain MR and CT within 12 months before autopsy that showed leptomeningeal melanin. For the normal imaging study, brain MR was done on 74 patients (31 bl...

When integumentary tissue pigments are contained in chromatophores, tissue color might not depend exclusively on the amount of pigment. Whether coloration does or does not reflect pigment concentration may be very significant for intraspecific communication, for example when pigment concentration provides fitness-related information. We studied the pigment responsible for the orange/red ventral...