We revisited a classic study of morphological variation in the oldfield mouse (Peromyscus polionotus) to estimate the strength of selection acting on pigmentation patterns and to identify the underlying genes. We measured 215 specimens collected by Francis Sumner in the 1920s from eight populations across a 155-km, environmentally variable transect from the white sands of Florida's Gulf coast t...

This Perspective provides a brief summary of the scientific evidence for often two-way links between hyperglycemia, including manifest diabetes mellitus (DM), and oral health. It delivers in nutshell examples current following manifestations along with any available effect opposite direction: periodontal diseases, caries/periapical periodontitis, tooth loss, peri-implantitis, dry mouth (xerosto...

Introduction It has been said that pigmentation of the skin is the most distinctive feature of Addison's disease (British Medical Journal, 1963) and that no other clinical feature is as useful diagnostically (Dunlop, 1963). Four cases are presented where no pigmentation was found. The difficulties in diagnosis are discussed and it is suggested that Addison's disease without pigmentation is comm...