This study aimed to profile the metabolites, piperine content, and biological activities (antioxidant, anti-inflammatory, anticancer, antibacterial, apoptotic cell) of 15 samples Piper nigrum L. from various geographic regions Thailand. UHPLC-QTOF-MS was applied establish alkaloid profiles P. samples. PCA HCA analysis showed that PN-1, PN-2, PN-11 sources differed significantly those other in t...

Piper nigrum (black pepper) is used in Indian traditional medicine and its main alkaloid, Piperine (PIP), presents antioxidant, antitumor neuroprotective pharmacological properties. This substance insoluble aqueous media can irritate the gastrointestinal tract. Aiming to avoid these inconvenient characteristics enable PIP oral administration, this study suggested microencapsulation through emul...

Pepper known as the king of spices is one most widely used spice in world, and it has its fair share medicinal properties well. It been traditional medicine for many centuries owing to apart from flavour pungent taste. Piperine important bioactive compound present different Piper species. Differences among three species common South India viz. <i>Piper nigrum</i>, longum</i>, ...

Background: “Streptococcus mutans” bacterial biofilm is known to be a major causative organism for dental plaque which acknowledged associated with biofilm. In this study we aim evaluate the effectiveness of natural compound “Piperine” on bacteria from One hundred cases Dental unit Of Rajshahi Medical College. Methods: This longitudinal was conducted in Molecular Pathology Insect Biotechnology ...

Abstract Background Plant secondary metabolites or mixtures in extracts essential oils are well known to enhance the activity binary mixtures. The present study is first report that thymol synergistically additively enhances of P. ribesioides and isolated compounds against S. exigua larvae at sublethal doses. Results Thymol was synergistic when mixed with hexane extract; however, if extract lev...