BACKGROUND The aim of the study was to assess the efficacy and safety of remifentanil for pain relief during external cephalic version (ECV) for breech presentation in nulliparous women at term. METHODS A total of 144 nulliparous women with singleton breech presentation were randomly divided into the intervention group and the placebo group, with 72 subjects in each group. The subjects in the...

Introduction: Shivering is a common side effect of central neuraxial anaesthesia. Intravenous pethidine commonly used in reducing shivering but has been associated with significant opioid effects. Dexamethasone as powerful anti-inflammatory and analgesia agent postulated to inhibit inflammatory mediators’ release thus inhibiting thermoregulatory centre, potentially attenuating post spinal shive...

Early postoperative pain from laparoscopic cholecystectomy is moderate. A transverses abdominis plane block (TAP) may be an attractive analgesic strategy for reducing opioid consumption and side effects. The study aimed to assess mean utilization in patients administered versus placebo undergoing cholecystectomy.This randomized controlled trial was conducted at the Department ofAnesthesiology, ...

To test the postulate that sex difference, sex steroids, and peptidyl secretagogues control GH autofeedback, 11 healthy postmenopausal women and 14 older men were each given 1) a single iv pulse of GH to enforce negative feedback and 2) continuous iv infusion of saline vs. combined GHRH/GHRP-2 to drive feedback escape during pharmacological estradiol (E(2); women) or testosterone (T; men) suppl...

BACKGROUND Pain after vaginal delivery can interfere with the activities of daily living. We hypothesized that epidural medication administered after delivery would be of benefit for acute postpartum pain management. The objective of this study was to assess whether epidural morphine after vaginal delivery would reduce the analgesic requirements for perineal pain. METHODS This randomized, dou...

OBJECTIVE To investigate the effect of molecular hydrogen (H2) in a rat model subjected to optic nerve crush (ONC). METHODS We tested the hypothesis that after optic nerve crush (ONC), retinal ganglion cell (RGC) could be protected by H₂. Rats in different groups received saline or hydrogen-rich saline every day for 14 days after ONC. Retinas from animals in each group underwent measurements ...

Background: Laparoscopy is an established method to perform major surgeries, with many advantages over open surgeries. Hysterectomy a common procedure performed increased use of laparoscopy, having postoperative pain management issue. Effective promotes early ambulation, lowering the risk DVT and PE.Methods: The present study aimed assess effect bupivacaine intraperitoneally during laparoscopic...

nano-sized drugs have better distribution than their identical forms. magnesium is the cofactor of various enzymes in lipid and glucose metabolism. in this study the effect of nano-magnesium oxide (nano-mgo) on glucose concentration and lipid profile in diabetes induced mice was evaluated in 21 laboratory mice. mice were divided randomly into three equal groups (control, treatment and placebo)....