Resveratrol is a plant secondary metabolite commonly found in peanuts and grapevines with significant health benefits. Recombinant organisms can produce large amounts of resveratrol and, in this work, Escherichia coli BW27784 was used to produce resveratrol in bioreactors while monitoring cell physiology and plasmid stability through flow cytometry and real-time qPCR, respectively. Initially, t...

Tuberculosis remains one of the major infectious diseases, which continues to pose a major global health problem. Transgenic plants may serve as bioreactors to produce heterologous proteins including antibodies, antigens, and hormones. In the present study, a genetic construct has been designed that comprises the Mycobacterium tuberculosis genes cfp10, esat6 and dIFN gene, which encode deltafer...

Membrane Bioreactors (MBRs) have attracted a significant attention of scientists and engineers in the past two decades. Improvement of membrane technologies coupled with experiences gained from application of membranes in different industrial processes have opened a gamut of opportunities in industrial wastewater treatment. The solidliquid separation that is conventionally carried out in gravit...

An increasing number of industrial plants integrate the anaerobic digestion (AD) organic fraction municipal solid waste (OFMSW) with a subsequent composting phase. To improve plant productivity, OFMSW digestate can be converted into carbonaceous material, called hydrocar (HC), through Hydrothermal Carbonization (HTC), and then composted together itself, to produce “hydrochar co-compost”. The ai...

This paper focuses on the recent research in the development of anaerobic membrane bioreactors in wastewater treatment. Anaerobic wastewater treatment technology is gaining increasing attention due to its capacity to convert wastewater BODs to usable biogas with relatively low energy consumption. The anaerobic membrane bioreactor (AnMBR), which is a combination of the anaerobic biological waste...

Background Hydrocyclones (HCs) have been recently extensively evaluated for their application in the separation of mammalian cells in perfusion bioreactors. The high centrifugal force derived within hydrocyclones is the key mechanism for cell separation inside such small-sized simple devices. This is usually accompanied by a very short residence time of the cells inside the separating equipment...

Textile wastewater represents challenging feed streams to be treated by membrane separation due to the complex composition and presence of reactive components. Here we fi rst briefl y present some characteristics of textile wastewater remediation where a key issue is (bio)fouling. We then present Membrane Bioreactors (MBRs) and Forward Osmosis (FO) membranes as both technologies have attracted ...

Tissue engineering involves using the principles of biology, chemistry and engineering to design a 'neotissue' that augments a malfunctioning in vivo tissue. The main requirements for functional engineered tissue include reparative cellular components that proliferate on a biocompatible scaffold grown within a bioreactor that provides specific biochemical and physical signals to regulate cell d...

Background Orbitally shaken flasks are commonly used at an early stage of bioprocess development with mammalian cells. In contrast to large-scale stirred-tank bioreactors, shaken flasks are usually operated in probe-independent bioprocesses, i.e. without strictly controlling the pH or dissolved oxygen concentration (DO). As a consequence, gas transfer issues are thought to limit the effectivene...

CURRENT SCIENCE, VOL. 108, NO. 10, 25 MAY 2015 1782 *A report on the Brainstorming session on ‘Somatic Embryogenesis and Use of Bioreactors’ organized by ICAR-Central Plantation Crops Research Institute, Kasaragod on 2 August 2014. on-line); http://mdgs.un.org/unsd/mdg/ SeriesDetail.aspx?srid=784 12. Hubbell, S. P., In Tropical Forest Diversity and Dynamism (eds Losos, E. C. and Leigh, E. G.), ...