نتایج جستجو برای: plant sterols

تعداد نتایج: 397863  

Journal: :The Journal of biological chemistry 2011
Jin Wang Nick Grishin Lisa Kinch Jonathan C Cohen Helen H Hobbs Xiao-Song Xie

ATP-binding cassette transporters ABCG5 (G5) and ABCG8 (G8) form a heterodimer that transports cholesterol and plant sterols from hepatocytes into bile. Mutations that inactivate G5 or G8 cause hypercholesterolemia and premature atherosclerosis. We showed previously that the two nucleotide-binding domains (NBDs) in the heterodimer are not functionally equivalent; sterol transport is abolished b...

Journal: :Journal of virology 2010
Monika Sharma Zsuzsanna Sasvari Peter D Nagy

The replication of plus-strand RNA viruses depends on subcellular membranes. Recent genome-wide screens have revealed that the sterol biosynthesis genes ERG25 and ERG4 affected the replication of Tomato bushy stunt virus (TBSV) in a yeast model host. To further our understanding of the role of sterols in TBSV replication, we demonstrate that the downregulation of ERG25 or the inhibition of the ...

Journal: :The American Journal of Clinical Nutrition 2003

Journal: :Journal of Biological Chemistry 1938

Journal: :Plant physiology 1970
P H Jennings F P Zscheile B L Brannaman

Results of studies with polyene antibiotics have pointed to an interaction with membranes (1). These interactions were reported to occur specifically with sterols (2), and a sparing effect has been noticed upon addition of exogenous sterols (4). It has also been noted that certain phytotoxins produced by plant pathogens interact with plant cell membranes, affecting their permeability and occasi...

Journal: :European Journal of Clinical Nutrition 2007

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