Abstract Background Bony fusion rate was significantly lower in patients with type 3 Modic change than normal endplates. It is not known whether there are relevant differences efficiency among 2 sclerotic or non-sclerotic change, no change. Methods A retrospective study contained 196 lumbar segments 123 subjects undergoing posterior interbody (PLIF) pedicle screw instrumentation (PSI) to assess...

In this study, we developed a new pharmacophore-based interaction fingerprint (Pharm-IF) and examined its usefulness for in silico screening using machine learning techniques such as support vector machine (SVM) and random forest (RF) instead of similarity-based ranking. Using the docking results of PKA, SRC, cathepsin K, carbonic anhydrase II, and HIV-1 protease, the screening efficiencies of ...

Infrared (IR) planar laser-induced fluorescence (PLIF) techniques for imaging of carbon monoxide and carbon dioxide are reported. These diagnostics employ a tunable IR source to excite overtone and combination band transitions of CO and CO2, respectively, and one or two InSb focal plane arrays to collect fluorescence emitted via fundamental transitions from excited vibrational states. A brief o...

Flame–turbulence interactions are at the heart of modern combustion research as they have a major influence on efficiency, stability of operation and pollutant emissions. The problem remains a formidable challenge, and predictive modelling and the implementation of active control measures both rely on further fundamental measurements. Model burners with simple geometry offer an opportunity for ...

The Homogeneous Charge Compression Ignition (HCCI) combustion progress has been characterized by means of high-speed fuel tracer Planar Laser Induced Fluorescence (PLIF) combined with simultaneous chemiluminescence imaging. Imaging has been conducted using a high-speed laser and detector system. The system can acquire a sequence of eight images within less than one crank angle. The engine was r...