Actaea racemosa (black cohosh) has a history of traditional use in the treatment of general gynecological problems. However, the plant is known to be vulnerable to adulteration with other cohosh species. This study evaluated the use of shortwave infrared hyperspectral imaging (SWIR-HSI) in tandem with chemometric data analysis as a fast alternative method for the discrimination of four cohosh s...

Linear discriminant analysis (LDA) is a classical statistical approach for dimensionality reduction and classification. In many cases, the projection direction of the classical and extended LDA methods is not considered optimal for special applications. Herein we combine the Partial Least Squares (PLS) method with LDA algorithm, and then propose two improved methods, named LDA-PLS and ex-LDA-PL...

PLS univariate regression is a model linking a dependent variable y to a set X= {x1; : : : ; xp} of (numerical or categorical) explanatory variables. It can be obtained as a series of simple and multiple regressions. By taking advantage from the statistical tests associated with linear regression, it is feasible to select the signi6cant explanatory variables to include in PLS regression and to ...

A number of central auditory neurons exhibit paradoxical latency shift (PLS), a response characterized by longer response latencies at higher sound levels. PLS neurons are known to play a role in target ranging for echolocating bats that emit frequency-modulated sounds. We recently reported that early inhibition of unit's oscillatory discharges is critical for PLS in the inferior colliculus (IC...

BACKGROUND Additional urinary biomarkers for diabetic nephropathy (DN) are needed, providing early and reliable diagnosis and new insights into its mechanisms. Rigorous selection criteria and homogeneous study population may improve reproducibility of the proteomic approach. METHODS Long-term type 1 diabetes patients without metabolic comorbidities were included, 11 with sustained microalbumi...

" …wealth and greatness are mere trinkets of frivolous utility. […] It is this deception which rouses and keeps in continual motion the industry of mankind. " Adam Smith List of papers This thesis is based on the following papers, which are referred to in the text by their Roman numerals: Improving structure-based virtual screening by multivariate analysis of scoring data. bias of scoring funct...

The outcomes of clinical usefulness as a driver of wireless technology for Indian healthcare are reported here. Using both qualitative and quantitative techniques, 30 physicians were interviewed and 200 health professionals were surveyed. The outcomes established that in addition to technology factors, other factors such as clinical factors, administration factors and communication factors play...

The performance of a multispectral imaging system has been evaluated in monitoring aerobically packaged beef filet spoilage at different storage temperatures (0, 4, 8, 12, and 16°C). Spectral data in the visible and short wave near infrared area (405-970nm) were collected from the surface of meat samples and correlated with microbiological data (log counts), for total viable counts (TVCs), Pseu...

Um novo método espectrofotométrico, simples e sensível, foi descrito para determinação simultânea de urânio e tório. O método é baseado na formação de complexos de urânio e tório com Arsenazo III em pH 3,0. Todos os fatores que afetam a sensibilidade foram otimizados e o intervalo dinâmico linear para determinação de cada analito foi encontrado. A determinação simultânea de urânio e tório em mi...

Sensorial analysis of pineapple breads (conventionally baked, Cpb; fully baked frozen, Fpb and partially baked, Ppb) showed no significant differences in terms of aroma and taste. On the contrary, the scores for the overall quality between the partially baked and conventionally baked breads showed significant (p < 0.05) differences. At the same time, headspace analysis using a solid-phase micro...