This study aimed to investigate the associations of the serial changes of serum levels of various growth factors with liver regeneration after hepatectomy in healthy liver donors. Sixteen healthy liver donors who underwent conventional liver resection were included. Serum levels of various growth factors before hepatectomy and on postoperative day (POD) 1, 3, 5 and 7 were measured. Liver volume...

Thioredoxin (TRX) production has been shown to be induced by a variety of stresses. In this study, we examined TRX expression in lung tissues after canine lung transplantation to determine whether it could be induced by allogenic stimulations and could be used to diagnose early rejection. Thirty-five adult mongrel dogs were used in all. In group A, 24 dogs underwent allotransplantation of the l...

Recently we described a novel cell penetrating peptide, peptide for ocular delivery (POD) that could deliver small molecules including fluorescent dyes into retinal cells. The objective of the current study was to examine whether biologically relevant macromolecules such as proteins, genetically fused with POD could also be delivered into retinal tissues in vivo. We generated a POD-GFP fusion p...

BACKGROUND Postoperative delirium (POD) is a common and critical complication after cardiac surgery. However, the relationship between POD and postoperative physical frailty and the effect of both on long-term clinical outcomes have not been fully explored. OBJECTIVE We aimed to examine the associations among POD, postoperative frailty, and major adverse cardiac events (MACE). DESIGN This w...

BACKGROUND We have previously shown that a novel synthetic peptide for ocular delivery (POD) can efficiently compact DNA and deliver it to cells in vitro. This observation prompted us to develop use of POD as a nonviral vector in vivo. METHODS POD peptide was modified using poly(ethylene) glycol (PEG-POD) and used to compact DNA into nanoparticles that were then analysed using electron micros...

Wavefront measurements of a turbulent boundary layer were performed at the University of Notre Dame. Optical access windows to the tunnel were instrumented with 16 accelerometers to measure the tunnel-induced vibrations in the optical windows. A combination of spectral Proper Orthogonal Decomposition (POD) and Linear Stochastic Estimation (LSE) were used to remove vibration induced effects in t...

We present a framework for applying the method of Proper Orthogonal Decomposition (POD) and Galerkin projection to compressible fluids. For incompressible flows, only the kinematic variables are important, and the techniques are well known. In a compressible flow, both the kinematic and thermodynamic variables are dynamically important, and must be included in the configuration space. We introd...

The aims of this paper are to present concept and results of an innovative educational model approach based on ergonomics involvement in industrial project. First we present Cross disciplinary Problem solving Workshop by answering three questions:1) What is a CPW: A partnership between Universities and one or several companies, purposes of it are first to increase health, well being, companies ...