Web applications are constantly increasing both in complexity and number of offered features. In this paper we address the problem of estimating the effort required to develop dynamic web applications, which represents an emerging issue in the field of web engineering. In particular, we formalize a method which is based on the main ideas underlying COSMIC-FFP (Cosmic Full Function Point), which...

We discuss the counting statistics and current noise associated with the double Josephson quasiparticle resonance point in a superconducting single electron transistor. The counting statistics are in general phase-dependent, despite the fact that the average current has no dependence on phase. Focusing on parameter regimes where the counting statistics have no phase-dependence, we use a general...

The potencies of mammalian cell-derived recombinant human erythropoietin pharmaceutical preparations, from a total of five manufacturers, were assessed by in vivo bioassay using standardized protocols. Eight-week-old normocythemic mice received a single subcutaneous injection followed by blood sampling 96 h later or multiple daily injections with blood sampling 24 h after the last injection. Re...

Most of the rainflow counting methods are developed for uniaxial stress states. In this paper, a new method multiaxial states has been proposed. The proposed is two-step procedure based on modified three-point ASTM algorithm where normal ranges identified along with start and end indexes each range. For cycle, shear evaluated cycle points using minimum circumscribed circle method. compared to t...