The different attributes of the Patient Evaluation Measure (PEM) questionnaire were investigated in 80 patients with a fracture of the scaphoid. Assessments were made at 2, 8, 12, 26 and 52 weeks. Reliability was assessed by measurement of the internal consistency of the different questions in 275 completed PEM forms. Cronbach's alpha, which needs to lie between 0.7 and 0.9, was 0.9 for the PEM...

Pem is a member of the homeobox transcription factor family that is expressed in somatic cells in male and female reproductive tissues. In the murine testis, Pem is specifically expressed in Sertoli cells, where it is dramatically induced at the initiation of meiosis during the first wave of spermatogenesis and then later is restricted to stages IV-VIII of the seminiferous epithelial cycle. To ...

We conducted a phase II study of combination chemotherapy with carboplatin (Cb) and pemetrexed (Pem) followed by gefitinib (Gef) to determine the effects and toxicities in patients with non-small cell lung cancer (NSCLC) harboring sensitive EGFR mutation. Eligible patients received four courses of Cb at a dose corresponding to a target area under the curve equal to 6 mg/mL∙min and 500 mg/m2 Pem...

Although the compromised GSH status of children with edematous protein-energy malnutrition (PEM) has been documented, the in vivo kinetic mechanism(s) responsible for this is not known. To determine if decreased synthesis contributes to the alteration of GSH homeostasis, the fractional and absolute rates of synthesis of erythrocyte GSH were determined shortly after admission (study 1), approxim...

BACKGROUND Pemetrexed (PEM) is a new-generation multitargeted antifolate agent with a demonstrated broad-spectrum activity in several types of human cancers, including non-small cell lung cancer (NSCLC) and mesothelioma. Major side effects include dose-limiting hematologic toxicities. PEM nephrotoxicity is well known; however, its frequency is considered to be low. CASE PRESENTATION Here we r...

In order to present a new and high performance structure of PEM fuel cell and study the influence of the flow direction and distribution on the rate of reactants diffusion, three novel models of vertical reactant flow injection into the anode and cathode reaction area field have been introduced. They consist of one inlet and two inlets and also a continuous channel. The governing equations on t...

We study the relativistically expanding electronpositron pair plasma formed by the process of vacuum polarization around an electromagnetic black hole (EMBH). Such processes can occur for EMBH’s with mass all the way up to 6 · 105M . Beginning with a idealized model of a ReissnerNordstrom EMBH with charge to mass ratio ξ = 0.1, numerical hydrodynamic calculations are made to model the expansion...

Pediatric Emergency Medicine (PEM) was introduced in Rhode Island in 1985, the year after the establishment of the federal EMS-C program designed to assist states in improving emergency medical care for children. Based at Rhode Island Hospital, PEM began as a fledgling subspecialty when DR. WILLIAM LEWANDER was recruited as Rhode Island’s first PEM subspecialist by the divisions of Emergency Me...

Despite the continued development of advanced algorithms for phylogeny reconstruction, the assessment of topological accuracy remains a challenging problem. New tools are needed to assist researchers in the prediction and evaluation of phylogenetic performance, particularly when short alignments are considered. We present a probabilistic analysis of quartet accuracy by the four-point method (FP...

The fundamental matrix plays an important role in the field of computer vision. How to estimate it accurately has become a major subject. In this paper, an improved approach based on the 7-point algorithm is presented. In this method, initial estimations of the fundamental matrix are provided by the 7-point algorithm. Then an optimal fundamental matrix will be selected which offers relatively l...