BACKGROUND Nigeria remains one of only three polio-endemic countries in the world. In 2016, after an absence of 2 years, wild poliovirus serotype 1 was again detected in North-Eastern Nigeria. To better guide programmatic action, we assessed the immunity status of infants and children in Borno and Yobe states, and evaluated the impact of recently introduced inactivated poliovirus vaccine (IPV) ...

The Western world has been polio-free for decades; however, many are affected by the stigmata of polio in several countries, including India. While general anesthesia (GA) and subarachnoid block (SAB) have used successfully widely, all those cases were mostly done with relatively older drugs without additives. Therefore, further literature is needed to note effect newer anesthetic agents on pos...

In this paper, a bilinear mathematical model of ordinary differential equations is introduced to investigate the transmission dynamics of polio virus in Nigeria. The effect of vaccines versus environmental clean-up efforts on disease transmission is discussed. In the modeling process, Monte Carlo simulations were employed to approximate the values of three unknown parameters. Transmission is as...

Polio vaccinators and law enforcement officials protecting them, have been killed in the line of duty since 2012 in Pakistan. This study was conducted to determine the opinions of university students in Islamabad and Rawalpindi, regarding the importance of polio vaccination, and the role of international donor agencies. Nine hundred forty-six students participated in this study; 833 (88.1%) stu...

Since 1988, when the World Health Assembly resolved to eradicate polio, the number of polio cases worldwide has decreased from 350,000 to fewer than 800 cases in 2003. This was achieved through high vaccination coverage, augmented by quality surveillance for acute flaccid paralysis (AFP) and mop-up vaccination campaigns. Although the European region was certified “poliofree” in 2002, as long as...

BACKGROUND Pakistan faces huge challenges in eradicating polio due to widespread poliovirus transmission and security challenges. Innovative interventions are urgently needed to strengthen community buy-in, to increase the coverage of oral polio vaccine (OPV) and other routine immunisations, and to enhance immunity through the introduction of inactivated polio vaccine (IPV) in combination with ...

poliomyelitis, an acute viral infectious disease caused by poliovirus, still remains a public health problem in developing countries. despite the global effort to eradicate polio, continuing the polio immunization with a potent and safe vaccine is essential. for accurate vaccine evaluation, three types of cell lines including hela, hep2c and vero were evaluated and compared using two methods of...

a serum survey was conducted to determine the immune status of children 2 months to 6 years old to polio virus type i, ii and iii related to the history of oral polio vaccination in fashapouye (a rural area in the south of teheran). 566 serum samples were obtained from children in 9 different villages and microneutra lization test was performed on 1;10 dilution of these sera. the study revealed...

The study reported in this article was conducted to propose a set graphical and analytical tools and assess their clinical utility by analyzing gait kinematics and dynamics of polio survivors. Phase plane portraits and first return maps were used as graphical tools to detect abnormal patterns in the sagittal kinematics of polio gait. Two new scalar measures were introduced to assess the bilater...

Objective Few countries have tested the sensitivity of their polio surveillance systems, undertaken a comprehensive risk assessment or questioned whether existing polio surveillance strategies are the optimal surveillance at this stage of the global eradication initiative. To address this issue, a risk assessment and review of Australia’s polio surveillance systems were undertaken to assess the...