Flax/Poly-(lactide) non-woven composites are an alternative to conventional glass/poly-(propylene), offering a potentially lower environmental impact solution for the automotive industry. To understand this complex material, its detailed architecture and void distribution examined through 3D microtomography. Anisotropy in fibre orientation is also observed, further verified off-axis tensile tes...

Background Therapeutic management of Mycobacterium avium infection is inadequate due to patient non-compliance, lengthy treatment regimen, multidrug associated toxic side-effects etc. particularly in AIDS patients who are at a greater risk of developing mycobacterial infection. This study was designed to evaluate chemotherapeutic potential of poly D, L-lactide-co-glycolide nanoparticles against...

Recently, polymeric nanoparticles (NPs) have attracted enormous attention as targeted drug delivery vehicles.[1-4] Especially, biodegradable and biocompatible polymeric NPs comprised of poly(lactide-co-glycolide)-b-polyethyleneglycol (PLGA-PEG) block copolymers exhibit optimal physicochemical characteristics such as the ability to incorporate various targeting agents, enhanced immune evasion, c...

Submit Manuscript | http://medcraveonline.com HPLC-UV: High Performance Liquid Chromatography And Ultravioleta Detector; HPLC-DAD: High Performance Liquid Chromatography and Diode Array Detector; NCB: Blank Nanocapsules; NCLS: Nanocapsules Containing Essential Oil of L. Sidoides; ODS: Octadecylsilyl Groups; OELS: Essential Oil of Lippia Sidoides; PLGA: Poly D, L-Lactide-Co-Glycolyde; PTFE: Poly...

Nitrile oxide 1,3 dipolar cycloaddition is a simple and powerful coupling methodology. However, the self-dimerization of nitrile oxides has prevented the widespread use of this strategy for macromolecular coupling. By combining an in situ nitrile oxide generation with a highly reactive activated dipolarophile, we have overcome these obstacles and present a metal-free macromolecular coupling str...

Biomaterials based on the polymers of lactic acid and glycolic acid and their copolymers are used or studied extensively as implantable devices for drug delivery, tissue engineering and other biomedical applications. Although these polymers have shown good biocompatibility, concerns have been raised regarding their acidic degradation products, which have important implications for long-term imp...