A stereospecific palladium-catalyzed N-vinylation of azaheterocycles with vinyl triflates is described. Cyclic and acyclic vinyl triflates along with nonnucleophilic azaheterocycles were found to be substrates for this palladium-catalyzed synthesis of N-vinyl pyrrole and indole derivatives.

Herein the nucleophilic addition of Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate, a stable and easy-to-handle reagent, to alkynes is described. This reaction provides trifluoromethylselenylated vinyl sulfones with good results and the method was extended also to higher fluorinated homologs. The obtained compounds are valuable building blocks for further syntheses of fluoroalkylselenolat...

G raham Hutchings of Cardiff University made a discovery in 1982 that came to define his career. He predicted that golddespite its reputation for being inertshould be an excellent catalyst for an industrial reaction that makes vinyl chloride monomer (VCM, or chloroethene), used to produce one of the world’s most ubiquitous plastics, polyvinyl chloride (PVC). More than three decades later, Hut...

A trinuclear gold(I)-oxo complex, [(Ph3PAu)3O]BF4, serves as the catalyst for the stereocontrolled synthesis of 2-hydroxy-3,6-dihydropyrans from propargyl vinyl ethers. Importantly, the rearrangement proceeds with excellent diastereoselectivity, and the rearrangement of chiral nonracemic propargyl vinyl ethers proceeds with excellent chirality transfer to furnish enantioenriched pyrans. Additio...

Dialkyl dithiophosphates selectively ring open vinyl oxetanes in excellent yields under mild reaction conditions to form useful allylic thiophosphate products with high Z-selectivity.

Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts cyclizations, giving access to iodoindenopyridines. Application of the vinyl halides in cross-coupling reactions has been explored, and mechanistic aspects of the cyclization are...

A gold-catalyzed formal [4+2] cycloaddition of vinyl indoles and N-allenamides leading to tetrahydrocarbazoles is described. Moreover, new multicomponent reactions of vinyl indoles with two allene molecules are reported.

Thiodiglycolic acid (TdGA) is the major metabolite of vinyl chloride monomer (VCM) detected in human urine. Although urinary TdGA has been reported to be associated with ambient VCM exposure, the relationship between urinary TdGA and a low level of air VCM is not clear. Questionnaires were administered to 16 polyvinyl chloride manufacturing workers to obtain a detailed history of occupation and...

A novel photoluminescent supramolecular hyperbranched polymer (SHP) without conventional chromophores was constructed for the first time by inclusion complexation between α-cyclodextrin and diethylenetriamine. The SHP showed wide-band fluorescence dependent upon the excitation wavelength.

Expansion of black-tailed prairie dog (Cynomys ludovicianus) colonies on public and private lands can result in damage to property. Physical barriers to prairie dogs can be used to minimize human–wildlife conflicts. We evaluated 17 existing barriers in the Fort Collins and Boulder, Colorado, areas. Most barriers were made of a single row of vinyl material; these barriers sustained high levels o...