The nutritional benefits of pomegranate have attracted great scientific interest. The pomegranate, including the pomegranate peel, has been used worldwide for many years as a fruit with medicinal activity, mostly antioxidant properties. Among chronic diseases, osteoporosis, which is associated with bone remodelling impairment leading to progressive bone loss, could eventually benefit from antio...

Hydrolyzable tannins (HTs) play important roles in plant herbivore deterrence and promotion of human health. A critical step in HT production is the formation of 1-O-galloyl-β-D-glucopyranoside (β-glucogallin, ester-linked gallic acid and glucose) by a UDP-glucosyltransferase (UGT) activity. We cloned and biochemically characterized four candidate UGTs from pomegranate (Punica granatum), of whi...

OBJECTIVES Food or drinks may significantly alter the pharmacokinetics and pharmacodynamics of drugs which may lead to adverse events. A drug such as metformin is widely used to regulate plasma glucose level and pomegranate and licorice have been identified to help in type-2 diabetes management. However, the interactions of the latter on metformin pharmacokinetics were not studied. Therefore, w...

Present study was performed to investigate the effect of Citrus limon and Pomegranate juices alone and their combinations on blood glucose and plasma insulin levels in alloxan induced diabetic rats as compared to diabetic control. Decrease in blood glucose level by Citrus limon was highly significant in dose dependant manner but there was highly significant increase in plasma insulin levels at ...

Although only recently Punica granatum (pomegranate) has been acclaimed for its health benefits, this fruit has long been cultivated and consumed, as a fresh fruit or in the form of beverage, especially in the Mediterranean region. In the present study, the antioxidant effects of the methanolic extract of pomegranate peels (MEPP) and pomegranate juice (PJ) were evaluated in normal male rats. Al...

BACKGROUND Atherosclerosis is enhanced in arterial segments exposed to disturbed flow. Perturbed shear stress increases the expression of oxidation-sensitive responsive genes (such as ELK-1 and p-CREB). Polyphenolic antioxidants contained in the juice derived from the pomegranate contribute to the reduction of oxidative stress and atherogenesis during disturbed shear stress. AIM OF THE STUDY ...

Prostate cancer is the second leading cause of cancer deaths in men in the United States. There is a major need for less toxic but yet effective therapies to treat prostate cancer. Pomegranate fruit from the tree Punica granatum has been used for centuries for medicinal purposes and is described as "nature's power fruit". Recent research has shown that pomegranate juice (PJ) and/or pomegranate ...

BACKGROUND Pomegranate fruit has been shown to exhibit the inhibitory activity against prostate cancer and lung cancer in vitro and in vivo, which might be a resource for chemoprevention and chemotherapy of cancer. Our previous documented findings indicated that treatment of urinary bladder urothelial carcinoma cell with the ethanol extract isolated from the juice of pomegranate fruit grown in ...

Um procedimento melhorado para a síntese de ésteres ácido indol-2-acético em rendimentos excelentes foi obtido pela condensação de 2-halo aril aldeídos ou cetonas e isocianoacetato de etila usando líquido iônico sob irradiação de microondas controlada (100 W) a 50 C. Este método oferece um número de vantagens em termos de metodologia simples, com rendimento elevado num tempo de reação curto e e...

Background: Jelebu is one of Negeri Sembilan districts Malaysia, famous for its wide variety D. zibethinus. It also recognized as the top hotspot area consumers looking genuine Durian Kampung. This study aimed at discovering and recording significant morphological data in identification classification zibethinus fruit Jelebu. Methods: Fifty-three accessions durian were observed from January 202...