INTRODUCTION For many years, transurethral resection of the prostate (TURP) has been accepted as the gold standard to surgically alleviate obstructive voiding dysfunction in men with benign prostatic hyperplasia (BPH). This historical standard has been challenged repeatedly over the last decade by consistent data demonstrating the superiority of Holmium enucleation of the prostate (HoLEP). This...

BACKGROUND The gynecological laparoscopic surgery requires pneumoperitoneum (PP) with CO2 gas insufflation. CO2 PP may influence cardiac automic function (CAF). This study was conducted to assess its significance and the prolonged effects of CO2 PP on the activity of the cardiac autonomic function 24 hours after the operation by heart rate turbulence (HRT) and heart rate variability (HRV), firs...

BACKGROUND Low level light therapy (LLLT) is an attractive alternative to enhance wound healing. So far most studies are performed with red or infrared irradiation. However, we recently showed that blue light (470 nm) can significantly influence biological systems, improving perfusion by release of nitric oxide from nitrosyl complexes with haemoglobin in a skin flap model in rats. Here, we comp...

BACKGROUND AND OBJECTIVE More recently laparoscopic radical cystectomy (LRC) has increasingly been an attractive alternative to open radical cystectomy (ORC) and many centers have reported their early experiences in the treatment of bladder cancer. Evaluate the safety and efficacy of LRC compared with ORC in the treatment of bladder cancer. METHODS A systematic search of Medline, Scopus, and ...

Introduction Current understanding of the secondary effects of brain surgery, both conventional and irradiative, is largely limited to clinical observations. Studies of post-operative imaging data have mainly concentrated on brain atrophy following radiotherapy and/or chemotherapy [ 1,2]. We have investigated the effect of conventional surgery on the unresected brain tissue based on the compari...

Recent advances to the adaptive optics scanning light ophthalmoscope (AOSLO) have enabled finer in vivo assessment of the human retinal microvasculature. AOSLO confocal reflectance imaging has been coupled with oral fluorescein angiography (FA), enabling simultaneous acquisition of structural and perfusion images. AOSLO offset pinhole (OP) imaging combined with motion contrast post-processing t...

OBJECTIVES To evaluate the overall efficacy and safety of endoscopic enucleation of the prostate (EP) vs open prostatectomy (OP) for large benign prostatic hyperplasia (BPH). METHODS We conducted an electronic search of PubMed/Medline, EMBASE, The Cochrane Library, and Web of Science to detect all relevant randomized controlled trials (RCTs) comparing EP with OP. A meta-analysis was performed...

BACKGROUND Osteoporotic fractures frequently require inpatient care, and are associated with elevated risks of morbidity, mortality, and re-hospitalization. A comprehensive evaluation of healthcare costs, resource utilization, and outcomes associated with osteoporosis (OP)-related fractures treated in US hospitals was undertaken. METHODS A retrospective analysis using the Premier Perspective ...

HSCT: Hematopoietic Stem Cell Transplantation; GVHD: GraftVersus-Host-Disease; DAH: Diffuse Alveolar Hemorrhage; ARDS: Acute Respiratory Distress Syndrome; RSV: Respiratory Syncytial Virus; CMV: Cytomegalovirus; HLA: Human Leucocyte Antigen; PCR: Polymerase Chain Reaction; IPS: Idiopathic Pneumonia Syndrome; OP: Organizing Pneumonia; BOOP: Bronchiolitis Obliterans Organizing Pneumonia; COP: Cry...

BACKGROUND Increased pulmonary vascular resistance (PVR) because of congenital heart disease (CHD) may be caused by a dysfunction in endogenous pulmonary endothelial nitric oxide (NO) production. In other forms of pulmonary vascular disease with increased PVR, an elevated activity of a phosphodiesterase type 5 (PDE-5), responsible for the degradation of cyclic guanidine monophosphate (cGMP), th...