INTRODUCTION    Pentraxin3 (PTX3) play an important role in the inflammatory response, taking part in recognizing pathogens and damaged tissues. OBJECTIVES    The aim of the study was to assess the relationship between PTX3 levels and all-cause and cardiovascular (CV) mortality in chronic kidney disease (CKD) patients during five-year observation period.  PATIENTS AND METHODS    The study compr...

To make an informed decision on renal replacement therapy, patients should receive education about dialysis options in a structured program covering all modalities. Many patients do not receive such education, and there is disparity in the information they receive. This review aims to compile evidence on effective components of predialysis education programs as related to modality choice and ou...

background beta-2 microglobulin (b2m) is considered as a surrogate marker for middle molecule uremic toxins and a key component in dialysis-related amyloidosis. however, few studies have evaluated role of b2m in patients with chronic kidney disease (ckd). objectives the purpose of this study was to evaluate the association of plasma b2m level with some metabolic and cardiac performance factors ...

background this retrospective study aimed to determine the epidemiologic characteristics and risk factors of chronic kidney diseases (ckd) in patients < 18 years old at a single referral center. materials and methods in a hospital-based case control study, 66 ckd patients less than 18 years old were compared to 81 control patients (also under 18) without ckd. a patient was defined as a ckd case...

Potassium homeostasis is generally well maintained in patients with advanced CKD until the GFR falls below 10–15 ml/min. Loss of nephron mass is counterbalanced by an adaptive increase in the secretory rate of K1 in remaining nephrons, such that fractional excretion of K1 is increased. In a study of normokalemic patients with stage 4 CKD, the fractional excretion of K1 was 126% compared with 26...

To elucidate the nature of altered cellular immunity seen in patients with chronic renal failure, the values of interleukin-2 (IL-2), a kind of lymphokine, and T-cell colony forming units were measured in controls (N = 10), predialysis uremic patients (N = 14), patients undergoing chronic hemodialysis (HD, N = 11) and patients on continuous ambulatory peritoneal dialysis (CAPD, N = 9). Dialytic...

background in the past few decades, chronic kidney disease (ckd) - a disease with progressive decline in renal function - has become an important problem of global public health, not only in developed countries, but also in developing countries with less economic power. objectives in this study, ckd progression to death or end stage renal disease (esrd) in elderly iranian patients was compared ...