In this paper, a general framework for image contrast enhancement algorithm based on an optimization problem is presented. Through this optimization, the intensities can be better distributed. The algorithm is based on the facts that the histogram of the enhanced image is close to the input image histogram and uniform distribution, simultaneously. Based on this fact, we obtain a closed form opt...

Circular RNA (circRNA) is a type of single-stranded with closed circular structure. Recent studies have shown that circRNA has relatively more stable structure than its linear counterparts. The become biological marker in medicine and plays crucial role disease prediction. However, traditional experiments are often time-consuming laborious. More researchers taking computational approaches to pr...

Contrast enhancement is an important factor in the image preprocessing step. One of the widely accepted contrast enhancement method is the histogram equalization. Although histogram equalization achieves comparatively better performance on almost all types of image, global histogram equalization sometimes produces excessive visual deterioration. A new extension of bi-histogram equalization call...