O bservational studies in humans and experimental studies in animals provide strong evidence that abnormalities in circulating angiogenic factors play a pathogenic role in pre-eclampsia. 1 Numerous angiogenic factor abnormalities have been noted in preeclampsia, but the factors studied most extensively are the antiangiogenic protein, soluble fms-like protein kinase 1 (sFlt1), and the proangioge...

Introduction: Pre-eclampsia is one of the complexities of maternal and neonatal health. There are several similarities between pre-eclampsia and atherosclerosis. The relation between chronic Chlamydia pneumoniae infections with atherosclerosis has been shown previously. This study has been done to determine the connection between pathogenesis and onset time of pre-eclampsia and chronic Chlamydi...

Pre-eclampsia is a pregnancy-specific syndrome that may be dangerous especially to the fetus. Different cytokines have been found to be elevated in women with pre-eclampsia and may have possible roles in the development of this disorder. Alleles of the interleukin-l-beta (IL-lβ) and tumor necrosis factor alpha (TNF-α) genes are associated with pr-eeclampsia in several studies in different popul...

BACKGROUND AND PURPOSE Preeclampsia affects 3% to 8% of pregnancies and increases risk of pregnancy-associated stroke (PAS). Data are limited on which women with preeclampsia are at highest risk for PAS. METHODS Using billing data from the 2003 to 2012 New York State Department of Health inpatient database, we matched women with preeclampsia and PAS 1:3 to preeclamptic controls based on age a...

PREECLAMPSIA IS A PREGNANCYspecific form of hypertension that presents a major health problem worldwide. Preeclampsia complicates 5% to 8% of all pregnancies and increases both maternal and neonatal morbidity and mortality. The mainstay of therapy for preeclampsia remains clinical recognition through prenatal care and termination of the disease process with delivery. Maternal mortality has been...

Introduction. Cardiac failure during pregnancy is usually related to preeclampsia/eclampsia, rarely to hyperthyroidism. While hyperthyroidism can easily lead to hypertensive cardiac failure and may harm the fetus, it is sometimes difficult to distinguish hyperthyroidism from normal pregnancy. Case Presentation. We encountered a case of 41-year-old pregnant woman with hypertensive cardiac failur...

Preeclampsia is a common disease of pregnancy characterized by the presence of hypertension and commitment of many organs, including the brain, secondary to generalized endothelial dysfunction. Its etiology is not known precisely, but it involved several factors, highlighting the renin angiotensin system (RAS), which would have an important role in the origin of multisystem involvement. This pa...

A 19-year-old primigravida delivered a normal full-term infant. She had been hypertensive during the latter stages of pregnancy. She developed cortical blindness, headache, and proteinuria. On physical examination, blood pressure was 170-180/100. The fundi were not well seen, vision was limited to light perception, and the pupils were equal and reactive to light. No sensory or motor deficit was...


 Purpose: To evaluate the impact of calcium and vitamin D (vit D) supplementation initiated at early pregnancy in high-risk women on reduction preeclampsia risk.
 Methods: This prospective cohort study involved 492 pregnant who had experienced pre-eclampsia or eclampsia their current (high risk) were either (1000 mg/day) as well vit (400 IU/day) none. All included received standard d...