Seventeen female patients who underwent orthotopic liver transplantation between June 1973 and June 1987 became pregnant 5 months to 11 years after transplantation. Immunosuppression was maintained with combinations of prednisone, cycloeporine, and azathioprine prior to and during pregnancy. One patient discontinued immunosuppression after knowledge of pregnancy, taking only azathioprine sporad...

An increased excretion of urinary formiminoglutamic acid (FIGLU) following an oral dose of histidine has been reported in various conditions other than folic acid deficiency,1 viz., vitamin B12 deficiency,2 hepatic cirrhosis,3,4 malabsorption syndrome,4 megaloblastic anemia associated with pregnancy and malnutrition,5 hemolytic anemia,6 iron-deficiency anemia,5 neoplastic disease,6 thyrotoxicos...

A variety of in utero factors have been associated with risk of adult cancers, particularly birth weight, toxemia, and gestational age. These factors are thought to reflect hormonal exposures during pregnancy. We hypothesized that the prenatal hormonal milieu may explain part of the variation in cancer rates across ethnic groups, for example, the higher incidence of breast cancer in the Caucasi...

The pre-eclamptic toxaemia of pregnancy is such a controversial subject that it is difficult to approach it from any angle without entering into the theory of aetiology ; and to enter into the aetiology is to plunge at once into a bottomless bog. Therefore it is proposed here to avoid theory as much as possible and stick to facts. Unfortunately, in order that the treatment may be understood tho...