Premenstrual dysphoric disorder (PMDD) affects 3-8% of women of reproductive age and is characterized by severe mood symptoms that cause important functional impairment. Serotonergic antidepressants appear to be an effective treatment for this disorder. The purpose of this study was to collect evidence on the efficacy and tolerability of duloxetine, a dual reuptake inhibitor of serotonin and no...

Ovarian cyclicity is a prerequisite for premenstrual dysphoria (PMD), as illustrated by the fact that this condition is effectively eliminated by ovariectomy or by treatment with a GnRH agonist. Despite the possibility of differences in ovarian function between women with and without PMD, no study comparing ovarian morphology in these two groups has ever been published. Fifty-two women were rec...

The cyclical variation of ovarian hormones during the menstrual cycle has been implicated as causative factor for many psychological and physical symptoms referred premenstrual syndrome (PMS) causing varying degree stress in females. This study is aimed to find out whether might cause any alteration visual reaction time (VRT) pre-menstrual post-menstrual phase. Reaction an efficient non-invasiv...

Blood-oxygenation-level-dependent functional magnetic resonance imaging is a noninvasive technique that has become increasingly popular in the neurosciences. It measures the proportion of oxygenated haemoglobin in specific areas of the brain, mirroring blood flow and therefore function. Here we review how the findings from functional studies impact on areas of gynaecological practice as diverse...

Madam I am somewhat concerned that in the same issue of the Journal as the statistical paper entitled ‘Size does matter’1 there was an Overview on ‘Homeopathy treatments for premenstrual symptoms’2 which may be considered to have depended on evidence that contradicted the statistical paper. I would be grateful for your opinion as to the reliability of the one clinical trial by Yakir et al.3, wh...

Madam I am somewhat concerned that in the same issue of the Journal as the statistical paper entitled ‘Size does matter’1 there was an Overview on ‘Homeopathy treatments for premenstrual symptoms’2 which may be considered to have depended on evidence that contradicted the statistical paper. I would be grateful for your opinion as to the reliability of the one clinical trial by Yakir et al.3, wh...

Premenstrual syndrome and premenstrual dysphoric disorder (PMDD) seem to form a severity continuum with no clear-cut boundary. However, since the American Psychiatric Association proposed the research criteria for PMDD in 1994, there has been no agreement about the symptomatic constellation that constitutes this syndrome. The objective of the present study was to establish the core latent struc...

Background: The global incidence of premenstrual syndrome (PMS) and dysphoric disorder (PMDD) is increasing, with increasing suicide reports. However, the bibliometric analysis research on PMS PMDD rare. We aimed to evaluate scientific output explore their hotspots frontiers from 1945 2018 using a methodology. Methods: Articles between were retrieved Web Science Core Collection (WoSCC). used me...