Aim: In this study, histological changes in stomach during prenatal and postnatal development were examined. Material and Methods: In this study, 34 female Wistar Albino rats weighing 200-250 g, obtained from Inonu University Experimental Animal Research Lab were used. Stomach samples obtained from prenatal 7,10,14,17, 20 days old fetuses and from postnatal 5,10,15,20 days old newly born and yo...

Several studies have shown the disruptive effects of non-competitive N-methyl-d-aspartate (NMDA) receptor antagonists on neurobehavioural development. Based on the neurodevelopment hypothesis of schizophrenia, there is growing interest in animal models treated with NMDA antagonists at developing stages to investigate the pathogenesis of psychological disturbances in humans. Previous studies hav...

PRENATAL STRESS ALTERS SINGLE-TRIAL CONDITIONED PLACE PREFERENCE IN ADOLESCENT RATS Stephanie L. Karsner, M.A. George Mason University, 2011 Thesis Director: Dr. Robert F. Smith Early environmental and behavioral experiences can affect development during adolescence and even adulthood. Prenatal effects can result in lasting changes on the nervous system and behavior. Gestational stress has been...

The effect of the introduction of chorionic villus sampling on the utilization rate of prenatal diagnosis in advanced maternal age was studied during the period 1 January 1985-1 January 1991. On the first of January 1985, the age limit for prenatal diagnosis in The Netherlands was lowered from 38 to 36 years of age. The overall uptake rate during the studied period increased significantly, but ...

The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain plasticity and development. Here we show that the fetal transcriptome, through microRNA (miRNA) regulation, responds to prenatal stress in association with epigenetic signatures o...

OBJECTIVES Expectant mothers experience marked hormone changes throughout the transition to parenthood. Although similar neuroendocrine pathways are thought to support maternal and paternal behavior, much less is known about prenatal hormone changes in expectant fathers, especially in humans. METHODS We examined longitudinal changes in salivary testosterone, cortisol, estradiol, and progester...

To study the seroprevalence of syphilis among pregnant women; attending their first prenatal examination, and the value of routine prenatal screening for syphilis at the Antenatal Clinic of King Abdulaziz University Hospital, Jeddah, Saudi Arabia. A retrospective analysis of the routine prenatal tests results of women attending for their first antenatal booking visits over a period of 3 years, ...

Adverse events during the prenatal and early postnatal period of life are associated with development of cardiovascular disease in adulthood. Prenatal exposure to excess testosterone (T) in sheep induces adverse reproductive and metabolic programming leading to polycystic ovarian syndrome, insulin resistance and hypertension in the female offspring. We hypothesized that prenatal T excess disrup...

This study examines the comparability between the last menstrual period-based and clinically estimated gestational age as collected on certificates of live birth. It explores whether sociodemographic or delivery characteristics influence their agreement and contrasts health status and health care utilization indicators, such as preterm, small for gestational age, and adequacy of prenatal care p...

The pediatrician who cares for a child with a birth defect or genetic disorder may be in the best position to alert the family to the possibility of a recurrence of the same or similar problems in future offspring. The family may wish to know about and may benefit from methods that convert probability statements about recurrence risks into more precise knowledge about a specific abnormality in ...