Background: Prenatal attachment affects maternal and infant health throughout life. Therefore, it is necessary to investigate the variables that may affect prenatal attachment. This study was carried out attachment, literacy, coping styles with stress among Turkish pregnant women by structural equation modeling. Methods:This a descriptive, analytical, cross-sectional study. It conducted via fac...

background: development of the central nervous system (cns) is dependent on interactions between genetic and epigenetic factors, some of which could affect the susceptibility of the developing brain to damaging insults. gestational stress has been shown as a potential factor associated with higher risk of developing certain neurological and psychiatric disorders. this study tested the hypothesi...

The early postpartum period lays important groundwork for later self-regulation as infants' dispositional traits interact with caregivers' co-regulatory behaviors to produce the earliest forms of self-regulation. Although emerging literature suggests that fetal exposure to maternal stress may be integral in determining child self-regulatory capacity, the complex pathways that characterize these...

Prenatal maternal stress affects offspring phenotype in numerous species including humans, but it is debated whether these effects are evolutionarily adaptive. Relating stress to adverse conditions, current explanations invoke either short-term developmental constraints on offspring phenotype resulting in decelerated growth to avoid starvation, or long-term predictive adaptive responses (PARs) ...

A growing body of evidence suggests the consumption of high-fat diet (HFD) during pregnancy to model maternal obesity and the associated increase in oxidative stress (OS), might act as powerful prenatal stressors, leading to adult stress-related metabolic or behavioral disorders. We hypothesized that administration of antioxidants throughout gestation might counteract the negative effects of pr...

O’Sullivan L, Cuffe JS, Koning A, Singh RR, Paravicini TM, Moritz KM. Excess prenatal corticosterone exposure results in albuminuria, sexspecific hypotension, and altered heart rate responses to restraint stress in aged adult mice. Am J Physiol Renal Physiol 308: F1065–F1073, 2015. First published February 25, 2015; doi:10.1152/ajprenal.00676.2014.—Exposure to excess glucocorticoids programs su...

BACKGROUND It has been suggested that prenatal stress contributes to the risk of obesity later in life. In a population-based cohort study, we examined whether prenatal stress related to maternal bereavement during pregnancy was associated with the risk of overweight in offspring during school age. METHODOLOGY/PRINCIPAL FINDINGS We followed 65,212 children born in Denmark from 1970-1989 who u...

Maternal prenatal stress has been found to be related to over-activity and/or dysregulation of the HPA-system in the offspring. These effects are more readily apparent in response to novel situations. The aim of the present report was to examine whether pregnancy stress predicted HPA-axis reactions of children to the first day of school after the summer break. Children of mothers with more pren...

Subchronic gestational stress leads to permanent modifications in the hippocampus-hypothalamus-pituitary-adrenal axis of offspring probably due to the increase in circulating glucocorticoids known to affect prenatal programming. The aim of this study was to investigate whether cell turnover is affected in the hippocampus-hypothalamus-pituitary axis by subchronic prenatal stress and the intracel...

Ethanol-induced neuro-developmental abnormalities are associated with impaired insulin and IGF signaling, and increased oxidative stress in CNS neurons. We examined the roles of ethanol and its principal toxic metabolite, acetaldehyde, as mediators of impaired insulin/IGF signaling and oxidative injury in immature cerebellar neurons. Cultures were exposed to 3.5mM acetaldehyde or 50mM ethanol ±...