We have previously shown that osteosarcomas (OS) have states of increased interstitial fluid pressure (IFP), which correlate with increased proliferation and chemosensitivity. In this study, we hypothesized that constitutively raised IFP in OS regulates angiogenesis. Sixteen patients with the clinical diagnosis of OS underwent blood flow and IFP readings by the wick-in-needle method at the time...

The practice of deep-braced excavation in congested urban environments involves frequently buried pipelines, which can exert a significant effect on the performance excavation. objective this paper is to investigate 12.5-m-deep-braced spanned by two shallowly large-diameter pressurized pipelines. A suspension structure installed within protect situ pipelines during construction. investigated pe...

•This is the first report of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in a woman with pseudomyxoma peritonei.•PIPAC achieved clinical and histological disease remission.•PIPAC with cisplatin and doxorubicin may be effective in pseudomyxoma peritonei.

A study on capstan partial pressure suits (PPSs) was conducted to determine their effects on pilots' operational performance on a series of ergonomic measures at different pressure levels using objective and subjective approaches. Tests of range of motion, operational performance and operational strength were carried out on ten male subjects wearing PPSs under 6 different pressure conditions. S...

The extraction yield, phenolic content, anthocyanin content and antioxidant activity of extracts from different varieties of red grapes, Cabernet Sauvignon, Merlot, Petit Verdot, Syrah, Tempranillo and Tintilla, using pressurized green solvents have been analyzed. Two techniques were studied and compared: supercritical fluid extraction (SFE) with CO2 + 20% ethanol and pressurized liquid extract...

Surgical-site infection is a common form of noscomial infection that can occur in fractures following internal fixation. Treatment of these infections has traditionally included preserving stable implants via debridement and antibiotic administration while the fracture is healing. Recent evidence indicated that this algorithm results in less-than-optimal rates of fracture union and infection er...

A reusable, arrayed interconnect capable of providing multiple simultaneous connections to and from a microfluidic device in an in-plane manner without the use of adhesives is presented. This method uses a ‘pin-and-socket’ design in which an SU-8 anchor houses multiple polydimethysiloxane septa (the socket) that each receive a syringe needle (the pin). A needle array containing multiple commerc...

The hydrothermal synthesis of zeolites carried out in batch reactors takes a time so long (typically, on the order of days) that the crystallization of zeolites has long been believed to be very slow in nature. We herein present a synthetic process for ZSM-5, an industrially important zeolite, on the order of seconds in a continuous flow reactor using pressurized hot water as a heating medium. ...

In this research, the effect of friction between the liquid metal and the sand mould wall and the effect of passage of liquid through a vertical bend and through a ceramic filter on the fluid flow and the melt velocity has been studied by measuring the velocity of the melt and direct observation of the liquid flow through the different parts of a naturally-pressurized running system. The fricti...

The study of two-phase fluid flow behavior in hydraulic structures such as pressurized flow tunnels, culverts, sewer pipes, junctions and other similar conduits is of great importance. A two-phase mixture flowing in a pipe can exhibit several interfacial geometries such as bubbles, slugs or films, depending on the fluid and hydrodynamic properties of flow. The main variables, giving rise to a v...