OBJECTIVES To determine whether human chorionic gonadotropin (hCG) detected in cervicovaginal secretions of patients with symptoms suggestive of preterm labor is a predictor of preterm birth. METHODS Women presenting to labor and delivery with symptoms of preterm labor were invited to participate. After collecting secretions with a cotton-tipped applicator from the posterior fornix and endoce...

AIM To assess the efficacy of oral ritodrine in the form of sustained-release capsules for maintenance of uterine quiescence after successful treatment of threatened preterm labor. METHODS We randomized 120 women with singleton pregnancy who were successfully treated for threatened preterm labor before 34 completed weeks to receive either maintenance tocolysis with two 40 mg ritodrine sustain...

BACKGROUND Preterm labor is the leading cause of infant morbidity and mortality so it may be necessary to administer tocolytics for treatment of it. OBJECTIVE The aim of this study was to compare the efficacy and safety of magnesium sulfate and nifedipine in the management of preterm labor. MATERIALS AND METHODS 100 women with documented preterm labor were randomly assigned to receive magne...

OBJECTIVE We sought to determine if preterm labor is associated with the degree of maternal hypoxia in pregnant women with community-acquired pneumonia but no other maternal diseases. METHODS We retrospectively reviewed the medical records of all antepartum patients admitted with a diagnosis of community-acquired pneumonia to an inner-city university hospital between 1983 and 1987. Included i...

Preterm birth remains the leading cause of perinatal mortality and morbidity. Evidence suggests that intrauterine infection plays an important role in the pathogenesis of preterm labor. This article reviews the clinical data supporting this theory and the cellular and biochemical mechanisms by which intrauterine infection may initiate uterine contractions. The clinical and laboratory methods of...

background: preterm birth is a major health problem that leads to infant morbidity and mortality. the main goal of this study was to find the relationship between social determinants of health and preterm delivery. methods: a prospective longitudinal cohort study was carried out on 500 pregnant women in their 24th to 28th gestational weeks in 2012. the pregnant women filled out a self-report qu...

introduction: regarding to the recent advances in assisted reproductive techniques (art), twin and multiple pregnancies have increased during past years. objective: this study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following art with spontaneous pregnancy. materials and methods: in this cross-sectional study which was performed in ghaem hospital...

The data described in this article is the subject of an article in the American Journal of Physiology: Cell Physiology, titled "The Human Uterine Smooth Muscle S-nitrosoproteome Fingerprint in Pregnancy, Labor, and Preterm Labor" (doi:10.1152/ajpcell.00198.2013) (Ulrich et al., 2013) [1]. The data described is a large scale mass spectrometry data set that defines the human uterine smooth muscle...

THE ROLE OF ALARMINS, INVARIANT NKT CELLS AND SENESCENCE IN THEPATHOPHYSIOLOGY OF STERILE INTRA-AMNIOTIC INFLAMMATIONbyOLESYA PLAZYOAugust 2016Advisor: Nardhy Gomez-Lopez, Ph.D.Major: Physiology (Reproductive Sciences Concentration)Degree: Doctor of PhilosophyPreterm birth is defined as the delivery of a live baby prior to the 37th week ofgestation. It is...

OBJECTIVE Spontaneous labor at term involves the activation of placental corticotropin-releasing hormone and the fetal adrenal axis, but the basis for extreme preterm labor is unknown. Our objective was to determine whether placental corticotropin-releasing hormone is activated in extreme preterm labor. STUDY DESIGN One thousand five hundred six mothers delivering at less than 28 weeks' gesta...