Mouse incisors are regenerative tissues that grow continuously throughout life. The renewal of dental epithelium-producing enamel matrix and/or induction of dentin formation by mesenchymal cells is performed by stem cells that reside in cervical loop of the incisor apex. However, little is known about the mechanisms of stem cell compartment formation. Recently, a mouse incisor was used as a mod...

The development of the lower incisor in the mouse was investigated from histological sections using computer-aided 3D reconstructions. At ED 13.0, the incisor was still at the bud stage. At ED 13.5, the initial cap was delimited by a short cervical loop, the development of which proceeded on the labial side, but was largely retarded on the medial side. This difference was maintained up to ED 15...

Incontinentia pigmenti achromians (IPA), first reported by Ito (Ito 1952), is a rare disease, involving the skin, hair, eyes, central nervous system, and musculoskeletal system. The cutaneous manifestations consist of macular hypopigmented whorls, streaks, and patches in a bilateral or unilateral distribution affecting almost any portion of the body surface. Central nervous system dysfunction, ...

Open bite (OB) is a generalized term, which could incorporate subgroups that react differently to vertical correction. The objectives of the present study were to detect vertical treatment changes in incomplete bite (IB: inter-incisor overlap with no lower incisor contact with teeth or palate) and OB (no inter-incisor overlap) groups compared with a complete bite (CB: inter-incisor overlap with...

OBJECTIVE Evaluation of the presence of the maxillary lateral incisor in the cleft in patients with complete unilateral cleft lip and palate treated with the use of various surgical protocols. MATERIAL AND METHODS A retrospective analysis was conducted as regards diagnostic models, panoramic radiographs and tooth images of the cleft of 75 patients with complete unilateral cleft lip and palate...

Any type of aesthetic correction in dental practice is always a challenging task, especially when it is complicated with cleft lip and alveolus. Careful examination and correct decision making at early stage of treatment and multi disciplinary approach is always necessary for long term success. This paper described a multidisciplinary approach in managing a 19-year-old female patient with unila...

Tooth regeneration by cell delivery encounters translational hurdles. We hypothesized that anatomically correct teeth can regenerate in scaffolds without cell transplantation. Novel, anatomically shaped human molar scaffolds and rat incisor scaffolds were fabricated by 3D bioprinting from a hybrid of poly-epsilon-caprolactone and hydroxyapatite with 200-microm-diameter interconnecting microchan...

STATEMENT OF THE PROBLEM The use of miniscrews has expedited the true maxillary incisor intrusion and has minimized untoward side effects such as labial tipping. PURPOSE The aim of this study was to assess the stress distribution in the periodontal ligament of maxillary incisors when addressed to different models of intrusion mechanics using miniscrews by employing finite element methods. The...

BACKGROUND This article describes the management of a complicated crown root fracture. CASE REPORT A young patient presented with a crown root fracture of the maxillary left central incisor with an oblique subgingival fracture line. A multidisciplinary treatment approach including endodontic treatment, orthodontic extrusion, surgical extraction and intra-alveolar repositioning was used to gai...

The continuously growing rodent incisor is a widely used model to investigate odontogenesis and mineralized tissue formation. This study focused on evaluating the mouse mandibular incisor as an experimental biological tool for analyzing in vivo the capacity of odontoblast-like progenitors or bioactive molecules to contribute to reparative dentinogenesis. We describe here a surgical procedure al...