results we identified no mutations in these patients in the three screened positions. conclusions to ensure that these genes play no role in the disease, evaluation of the non-coding regions of both the cyp1b1 and myoc genes is strongly recommended, since other genes are involved in the pathogenesis of glaucoma. patients and methods forty patients with poag were recruited from the ophthalmic di...

The primary open-angle glaucomas are a group of diseases that have in common characteristic morphological changes at the optic nerve head and retinal nerve fiber layer, progressive retinal ganglion cells death and characteristic visual field loss. The risk for primary open angle glaucoma rises continuously with the level of the intraocular pressure. The disease advances slowly and there are no ...

BACKGROUND 5-Fluorouracil, an antimetabolic agent, improves the success rate of trabeculectomies by inhibiting subconjunctival fibrosis. However, complications may be associated with early postoperative use. We investigated the outcome of needling revision with delayed subconjunctival 5-fluorouracil in failing filtering blebs after a trabeculectomy in patients with medically poorly controlled g...

The results of a 12-month blind randomised trial comparing the intraocular pressure lowering effect of timolol 0.25% with timolol 0.5% are presented. 27% of patients (22% of eyes) required additional antiglaucoma medication after a minimum time interval of 6 months to maintain an intraocular pressure less than 23 mmHg. The mean reduction in intraocular pressure (from pretreatment values) at 12 ...

Fifty-nine eyes undergoing combined cataract extraction and trabeculectomy were studied. The follow-up period ranged from 6 months to 2 years. The visual outcome and postoperative control of intraocular pressure have been compared in chronic open-angle, chronic closed-angle, and secondary glaucoma. Good results were obtained in both primary open- and closed-angle glaucoma, but not in secondary ...

PURPOSE To report the pattern of glaucoma among Saudi patients who were presented to King Abdul Aziz University Hospital (KAUH). METHODS All glaucoma or glaucoma suspect patients who were presented to KAUH from 2006 to 2008 were included; medical files of all patients were retrieved and evaluated through standardized international guidelines. Collected data included: age, sex, laterality, int...

BACKGROUND Angle closure glaucoma is emerging as a leading cause of blindness in Asia. OBJECTIVE To compare the ocular axial length of normal individuals and the subjects with primary angle closure glaucoma. This study has been conducted to determine axial length of eye as a risk factor of primary angle closure glaucoma. MATERIALS AND METHODS A cross-sectional comparative study was carried ...

BACKGROUND The aim of this study was to evaluate diagnostic parameters and analysis of their advantages and limitations in early diagnostics of primary open-angle glaucoma (POAG). Cup/disc ratio (C/D), nerve fiber index (NFI) and mean deviation of retinal sensitivity (MD) were considered. MATERIAL/METHODS Fifty primary open-angle glaucoma patients (95 eyes), 67 primary open-angle glaucoma sus...

Trabeculectomy surgery has been shown to lower intraocular pressure and is the most commonly performed glaucoma procedure worldwide. However, giving a patient a 'bleb for life' is not without consequences and the failure of trabeculectomy to control IOP in the long term is well documented. In some instances, such as in patients with exfoliative glaucoma or primary angle closure glaucoma, catara...