BACKGROUND Task specific tremors in musicians have been mainly described as primary bowing tremor in string instrumentalists in relatively small sample sizes. Our aim was to describe epidemiology, risk factors, phenomenology and treatment options of this disorder in 23 musicians of different instruments. METHODS We included 23 professional musicians (4 female, 19 male; mean age 51.5 ± 11.4 ye...

background: epilepsy is the second common neurologic disorder. although many antiepileptic drugs have been formulated to control the seizures, but not all seizures have been controlled by them. uncontrolled epilepsy can actually reduce the patients’ quality of life. objectives: identifying the proportion of adult intractable epilepsy among epileptic patients in an area in the north east of iran...

Trace organic compounds (TrOCs), mostly found in secondary effluents, have a potential impact on the environment, affecting surface water, groundwater, and especially aquatic ecosystems. The present study focuses on oxidation of five selected TrOCs in column experiments, by simulating Soil Aquifer Treatment (SAT) integrated with Fenton-like reaction, using Granular Ferric Hydroxide (GFH) as a c...

the present study has been directed to investigate ursodeoxycholic acid (udca) effect in children, to reduce the high liver transaminases induced by anticonvulsant drugs (drug induced hepatitis). this idea has been driven from cytoprotective and antioxidant properties of udca to be used in drug induced inflammation in liver. twenty two epileptic patients aged between 4 mo - 3 yr whom were under...

BACKGROUND Essential tremor (ET) is a common condition associated with significant physical and psychosocial disability. "Classic" ET is a clinical syndrome of action tremor in the upper limbs and less commonly the head, jaw, voice, trunk, or lower limbs. Current diagnostic criteria for ET exclude isolated vocal tremor (IVT). Failure to recognize IVT as a form of ET may contribute to misdiagnos...

Antiepileptic drugs (AEDs) are increasingly used for the treatment of several non-epileptic neurological conditions and psychiatric disorders. Most of the information available on the use of these agents in clinical disorders outside epilepsy is from case series, uncontrolled studies or small randomised clinical trials, and their apparent efficacy requires confirmation through well designed, la...

BACKGROUND This study explored whether antiepileptic drugs (AEDs) use increases the risk of hepatocellular carcinoma (HCC). METHODS We conducted a case-control study using data from the National Health Insurance system of Taiwan. The case group comprised 1,454 epilepsy patients with newly diagnosed HCC, and the control group comprised 1,448 epilepsy patients without HCC. Both groups had simil...

Blood (serum/plasma) antiepileptic drug (AED) therapeutic drug monitoring (TDM) has proven to be an invaluable surrogate marker for individualizing and optimizing the drug management of patients with epilepsy. Since 1989, there has been an exponential increase in AEDs with 23 currently licensed for clinical use, and recently, there has been renewed and extensive interest in the use of saliva as...

Case report. A 27-year-old woman presented with a movement disorder. She was born full term. She walked at 18 months, and speech development was delayed. Involuntary movements were first noted at 3 years with walking and increased in amplitude over time. Dystonia was first diagnosed at age 3. She had frequent falls due to involuntary myoclonic movements in the setting of lower extremity dystoni...

Valproic acid (VPA; Depakene#{174}; Depakote#{174}) is indicated for use both as the sole and adjunctive therapy in the treatment of simple (petit mal) and complex absence seizures. It may also be used adjunctively in patients with multiple seizure types, which includes absence seizures. Adjustment of VPA dosage in patients with convulsive disorders is routinely guided by measurements of total ...