There is a limited evidence base for the use of pro re nata (PRN) 'as required' psychotropic medication within acute mental health settings. This study aimed to explore expert opinion concerning issues and best practice for the prescribing and administration of psychotropic PRN medications within acute inpatient mental health settings. Eighteen experts participated in three Delphi rounds of a m...

As infants lose maternally derived antibody, they experience a period when antibody levels are insufficient to protect against measles yet may interfere with immunization. In Kangaba Mali, sera were collected from 89 2-8-month-old infants and 32 9-10-month-old infants without a history of measles or vaccination; post-vaccination sera were collected from 24 of the 9-10-month-old infants 3-5 week...

the future development of effective and safe antiretroviral agents—and the continued study of ways to maximize the utility of currently available therapies—are highly dependent on a scientific field that has evolved in recent years at an incredible rate: pharmacology. While The prn Notebook has published numerous articles focusing on the issues of pharmacokinetics (pk) and pharmacodynamics (pd)...

Up-to-date data are needed on the types of treatments used by psychiatrists and the reasons for use of particular treatments. Using 1997 American Psychiatric Association (APA) Practice Research Network (PRN) Study data on patients with schizophrenia and other psychotic disorders, we identified the characteristics of antipsychotic medications (APMs) currently being prescribed and factors associa...

We examined sensory-processing disorder (SPD) in children with cochlear implants and explored the relationship between SPD and duration of hearing loss or duration of cochlear implant use. Caregivers of 30 children completed the Sensory Profile Questionnaire (SPQ). Seventy percent of the children showed "at-risk" or "different" behaviors in one or more of five categories of the SPQ: auditory, v...

Neuroleptic malignant syndrome (NMS) is a rare life-threatening condition, usually induced by typical and atypical antipsychotics. A middle-aged woman with bipolar disorder and acute back pain due to multiple falls was admitted to the trauma ward of a general hospital. After 3 days, she suddenly developed signs and symptoms of NMS possibly caused by PRN injectable haloperidol, although the addi...

Position The Association of Women’s Health, Obstetric and Neonatal Nurses (AWHONN) believes that registered nurses (RNs) who are not licensed anesthesia care providers should monitor but not manage the delivery of analgesia and anesthesia by catheter techniques to pregnant women. These techniques include administration of analgesia and anesthesia via epidural, intrathecal, spinal and patient-co...

The article discusses various options for constructing binary generators of pseudo-random numbers (PRN) based on the so-called generalized Galois and Fibonacci matrices. terms "Galois matrix" "Fibonacci are borrowed from theory cryptography, in which linear feedback shift registers (LFSR) PRN according to schemes widely used. matrix generate identical sequences as LFSR generators. transition cl...