Astragalus species are medicinal plants which produce valuable secondary metabolites, especially cycloartane-type glycosides. In this study, stem and leaf explants of Astragalus trojanus were subjected to different plant growth regulators, environmental conditions and media compositions to identify their callus responses. Stem and leaf explants were cultured in Murashige and Skoog (MS) and wood...

The persisting drought in Iran, where the livestock are mostly fed by natural pastorlands, has caused a higher rate of sheep slaughter, thus an increase in the supply of meat and a reduction of the price in the Summer 2008. On the other hand, the higher slaughter diminished the available level of the cattle which in turn reduced the production capacity of the following year. This is inherent an...

Gut microbial dysbioses are linked to aberrant immune responses, which are often accompanied by abnormal production of inflammatory cytokines. As part of the Human Functional Genomics Project (HFGP), we investigate how differences in composition and function of gut microbial communities may contribute to inter-individual variation in cytokine responses to microbial stimulations in healthy human...

Managing Capacity Flexibility in Make-to-Order Production Environments Fehmi Tanrisever , Douglas Morrice , David Morton c a School of Industrial Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands b Red McCombs School of Business, The University of Texas at Austin, Austin, TX 78712 c Graduate Program in Operations Research and Industrial Engineering, The University of T...

The Cobb–Douglas function is today one of the most widely adopted assumptions in economic modeling, yet both its theoretical and empirical bases have long been under question. This paper builds an alternative function on very different (albeit also neoclassical) microfoundations aimed at both addressing those theoretical drawbacks and providing a better empirical fit than the Cobb–Douglas formu...

In this article, I investigate the capacity investment cost conditions where a multiproduct market leader may respond to a focus strategy entrant by using different strategies such as changing the product mix, production volumes, quality levels, and/or by investing in more capacity. The products offered in the market are quality differentiated and customers are heterogeneous in their willingnes...

PURPOSE: Various lines of evidence suggest that proinflammatory factors may play a role in tumor growth and metastasis, the leading cause of cancer-related mortality. However, most evidence originates from animal models, only few human studies reported an association between proinflammatory cytokines and death from cancer. Here, we investigated the association between circulating levels and inn...

Successful start-up firms make a valuable contribution to economic growth and development. Models that provide insight into the management of start-up firms are therefore important. We consider the problem of managing inventory and production capacity in a start-up manufacturing firm and argue that for such firms the objective of maximising the probability of the firm surviving is more appropri...

This paper explores the relationship between constrained capacity and supply chain performance. Six capacity constraint levels are studied under different inventory policies and information sharing strategies. The results suggest that an increment of production capacity, used in industry as local approach to manage increasing incoming orders, does not necessarily imply an improvement in custome...

n overview of techniques available to address capacity planning in the production data processing environment is presented. The production data processing system is briefly described and its capacity is quantijied. The measurement tools, reports, and data required to implement a capacity planning program are discussed. Modeling and prediction are placed in perspective with the overall objective...