نتایج جستجو برای: production platform

تعداد نتایج: 739566  

Journal: :Cell 2016
Keith Pardee Shimyn Slomovic Peter Q. Nguyen Jeong Wook Lee Nina Donghia Devin Burrill Tom Ferrante Fern R. McSorley Yoshikazu Furuta Andyna Vernet Michael Lewandowski Christopher N. Boddy Neel S. Joshi James J. Collins

Synthetic biology uses living cells as molecular foundries for the biosynthesis of drugs, therapeutic proteins, and other commodities. However, the need for specialized equipment and refrigeration for production and distribution poses a challenge for the delivery of these technologies to the field and to low-resource areas. Here, we present a portable platform that provides the means for on-sit...

2015
Avena C. Ross Lauren E. S. Gulland Pieter C. Dorrestein Bradley S. Moore

Marine pseudoalteromonads represent a very promising source of biologically important natural product molecules. To access and exploit the full chemical capacity of these cosmopolitan Gram-(-) bacteria, we sought to apply universal synthetic biology tools to capture, refactor, and express biosynthetic gene clusters for the production of complex organic compounds in reliable host organisms. Here...

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