Objective: To investigate the clinical efficacy of combination enhanced “Shou Tai Wan” soup and progesterone in treatment early pre-eclampsia miscarriage. Methods: 86 patients with miscarriage our hospital from July 2021 to 2022 were selected randomly divided into two groups 43 cases each. The control group was treated progesterone, while study an addition soup. effects changes inflammatory fac...

the aim of this study was to evaluate changes that occur in motility parameters of progesterone treated mouse spermatozoa during course of hyperactivation. mouse spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min of incubation. for each sperm, one second of movement of the head-midpiece junction was traced from the videotape and for each tracing sev...

Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post-in...

The present study aimed to investigate progesterone receptor (PR) gene expression in cumulus cells and their roles during meiotic resumption of porcine oocytes. The amount of PR-A or PR-B mRNA was analyzed by RT-PCR using primer sets for the PR-B region or the PR-A/B common region. The level of PR-B mRNA in cumulus cells was up-regulated by FSH and LH during the first 8 h of cultivation but the...

Introduction: Ghrelin increases growth hormone secretion and food intake. Growth hormone (GH), steroid hormones and opioids are involved in the regulation of food intake. So, they may have a role in the regulation of ghrelin secretion. We determined the effect of intravenous injections of progesterone, GH and morphine or co-administration of these hormones on ghrelin concentration and body w...

background: hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation. the current study was designed to evaluate dose-dependent effect of chlorpromazine (cpz) on hormonal changes and uterine horn histological structure in rats. moreover, the mammary glands were analyzed to show hyperprolactinemia-induced histological changes. methods: albino wistar r...

the sex hormone progesterone has been shown to improve outcomes in animal models and two early-phase trials involving patients with traumatic brain injury (tbi). the aim of this clinical study was to assess the effect of progesterone on the improvement of neurologic outcome in patients with diffuse and acute tbi. a prospective, randomized, double-blind trial of progesterone was conducted in our...

Background: Progesterone as a sex steroid hormone is thought to affect and prevent demyelination, but its role in promoting myelin repair is far less investigated. In this study, remyelinating potential of progesterone in corpus callosum was evaluated on an experimental model of MS.Methods: In this experimental study, adult male C57BL/6 mice were fed with 0.2% (w/w) cuprizone in ground breeder ...

In female rats, the onset of reproductive behavior depends on the sequential presence of estradiol followed by progesterone. Although treatment with high doses of estradiol has been shown to increase immunostaining for the Fos protein, an immediate early gene product that is expressed upon cellular activation, another report conflicts with this finding. However, the previous reports agree that ...