نتایج جستجو برای: progressive multiple sclerosis

تعداد نتایج: 887581  

Journal: :AJNR. American journal of neuroradiology 1998
J H van Waesberghe M A van Buchem M Filippi J A Castelijns M A Rocca R van der Boom C H Polman F Barkhof

BACKGROUND AND PURPOSES MR imaging is now widely used to monitor disease progression in patients with multiple sclerosis (MS). The purpose of this study was to explore the relationship between disability status and existing and new MR parameters in MS patients. METHODS Forty-one patients with clinically definitive MS were studied. MR imaging included T2- and T1-weighted imaging as well as gra...

2015
Juan Ignacio Rojas Liliana Patrucco Maria Trojano Alessandra Lugaresi Guillermo Izquierdo Helmut Butzkueven Vilija Jokubaitis Pierre Duquette Marc Girard Francois Grand’Maison Pierre Grammond Celia Oreja-Guevara Raymond Hupperts Cavit Boz Thor Petersen Roberto Bergamaschi Giorgio Giuliani Jeannette Lechner-Scott Michael Barnett Maria Edite Rio Vincent Van Pesch Maria Pia Amato Gerardo Iuliano Marcela Fiol Mark Slee Freek Verheul Ricardo Fernandez-Bolanos Dieter Poehlau Maria Laura Saladino Leontien Den Braber-Moerland Norma Deri Walter Oleschko-Arruda Jose Antonio Cabrera-Gomez Mark Paine Norbert Vella Ilya Kister Eli Skromne Aldo Savino Cameron Shaw Fraser Moore Steve Vucic Tatjana Petkovska-Boskova Elizabeth Alejandra Bacile Bacile Vetere Santiago Edgardo Cristiano

Limited data suggest that multiple sclerosis (MS) in Latin America (LA) could be less severe than in the rest of the world. The objective was to compare the course of MS between LA and other regions. METHODS Centers from 18 countries with >20 cases enrolled in the MSBase Registry participated. Patients with MS with a disease duration of >1 year and <30 years at time of EDSS measurement were e...

Journal: :Neurology 2016
Angelo Ghezzi Maria Pia Amato Naila Makhani Teri Shreiner Jutta Gärtner Silvia Tenembaum

Many disease-modifying therapies are currently available for adults with relapsing-remitting multiple sclerosis (MS) but none of them has been tested in pediatric MS in randomized placebo-controlled trials. At present, as suggested by observational studies and experts' guidelines, interferon-β and glatiramer acetate continue to be the standard first-line treatments for pediatric MS. Observation...

2012
Claudia Cristina Ferreira Vasconcelos Gutemberg Augusto Cruz dos Santos Luiz Claudio Thuler Solange Maria Camargo Regina Maria Papais Alvarenga

Background. Studies on the clinical course of multiple sclerosis have indicated that certain initial clinical factors are predictive of disease progression. Regions with a low prevalence for disease, which have environmental and genetic factors that differ from areas of high prevalence, lack studies on the progressive course and disabling characteristics of the disease. Objective. To analyse th...

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