BACKGROUND Addicted patients present difficulties for pain management because they have another problem besides their pain. Adding adjuvants to opioid pumps to intensify quality, control other problems, lengthen analgesia, and reduce side effects has been considered in the field. OBJECTIVES The objective of this study was to evaluate the analgesic effects of adding clonidine, promethazine, ch...

GENERIC NAME PAGE Brompheniramine 454 Carbinoxamine 454 Cetirizine 453 Chlorpheniramine 454 Cimetidine 455 Clemastine 454 Cromolyn sodium 455 Cyclizine 455 Cyproheptadine 454 Desloratadine 453 Dimenhydrinate 455 GENERIC NAME PAGE Diphenhydramine 454 Famotidine 455 Fexofenadine 453 Hydroxyzine 454 Loratadine 453 Meclizine 455 Nedocromil 455 Promethazine 455 Pyrilamine 455 Ranitidine 455 Tripelen...

The phenothiazine derivatives such as: promethazine, chlorpromazine and thioridazine hydrochlorides are used as psychotropic, neuroleptic, local anesthetics, anti-allergic and antiyomiting drugs [1]. The therapeutic interest in these compounds group justifies research to establish different analytical methods for the determination of these drugs in pharmaceutical preparations and biological sam...

Abuse of antitussive preparations is a continuing problem in the United States and throughout the world. Illicit, exploratory, or recreational use of dextromethorphan and codeine/promethazine cough syrups is widely described. This review describes the pharmacology, clinical effects, and management of toxicity from commonly abused antitussive formulations.

A double-blind study of 700 healthy children was done in an attempt to investigate the effectiveness of promethazine (Phenergan) with regard to the incidence and severity of ketamine-induced emergence phenomena. This study indicates that preoperative administration of Phenergan syrup is effective in reducing postoperative psychomimetic reactions, recovery time, patient apprehension, and the inc...

Children and adolescents with intellectual disability (commonly referred to as learning disability by the National Health Service (NHS) in the UK) have significantly higher rates of psychiatric morbidity than those without such disabilities (Emerson 2003). Recent major UK health planning documents have emphasised the role of local child and adolescent mental health services (CAMHS) in providing...

BACKGROUND Effects of the H1-antihistamine, cetirizine, were studied on daytime alertness and performance to establish whether the drug would be suitable for use by air personnel and others involved in skilled activity. METHODS The investigation was carried out in six healthy volunteers, and the effects of the drug (5, 10, and 15 mg) were studied on sleep latency, subjective sleepiness, digit...

To the Editor:-Anesthetic implications of neurofibromatosis may include airway, mediastid and vertebral neurofibromas, associated endocrine syndromes, and intracranial masses in 510% of patients. ’ Hydrocephalus is a rare manifestation of neurofibromatosis and is commonly descrihed during the first two decades of lie.’-* We present a case of acute postoperative hydrocephalus in a previously hea...