Benign prostatic hyperplasia is a histological diagnosis and the most frequent benign tumor in older men, its incidence strongly correlates with advanced age. Giant prostate enlargement (GPE), also known as giant hyperplasia, term given for severely enlarged prostates that weigh more than 500g. GPE cases reported literature less 30. We describe our experience of removing previously asymptomatic...

BACKGROUND AND PURPOSE Increased incidence of benign prostatic hyperplasia among insulin-resistant individuals suggests a role for hyperinsulinaemia in prostatic enlargement. We have already reported increased cell proliferation and enlargement of prostate gland in insulin-resistant rats. The present study aimed to elucidate the molecular mechanisms underlying the reversal of prostatic enlargem...

A PHASE II STUDY ASSESSING THE SAFETY AND EFFICACY OF A SINGLE TREATMENT OF 100 U, 200 U, or 300 U BOTOX® COMPARED WITH PLACEBO INJECTED INTO THE PROSTATE TO TREAT LOWER URINARY TRACT SYMPTOMS (LUTS) IN PATIENTS DUE TO BENIGN PROSTATIC HYPERPLASIA Trial ID: 191622-517-05 Coordination: CMX Research Inc. Trial design: A phase II study assessing the safety and effi cacy of a single treatment of BO...

Prostate cancer (PCa) is the most frequent neoplasic condition in males, but only 64-65% of the cases are sensitive to hormone therapy. The aim of this study was to investigate the neuroendocrine component of the prostatic carcinoma, in relation to the histopathological form and the degree of differentiation. Biopsies were obtained through transurethral resection, from 82 patients with prostate...