in recent years considerable interest has been focused on the plasma amino acid patterns as a possible index of protein malnutrition, in children. thus a change in the ratio of non-essential to essential amino acids is considered to be significant in the development of protein malnutrition. the present paper reports a simplified and rapid chromatographic procedure for the determination of this ...

A series of trials was conducted to determine the effects of supplemental rumen-protected methionine (RPMet) and lysine (RPLys) on nutrient metabolism and performance. In situ RPMet N disappearance was less than 4% following 48 h of incubation and was not affected (P greater than .05) by diet or resultant ruminal pH differences, indicating that RPMet was well protected from ruminal microbial de...

Proteins can be classified into four structural classes (all-α, all-β, α/β, α+β) according to their secondary structure composition. In this paper, we predict the structural class of a protein from its Amino Acid Composition (AAC) using Support Vector Machines (SVM). A protein can be represented by a 20 dimensional vector according to its AAC. In addition to the AAC, we have used another featur...

A series of fullerene substituted phenylalanine derivatives have been prepared by the condensation of 1,2-(4'-oxocyclohexano)fullerene with ester or Boc protected (4-amino)phenylalanine, H(2)NC(6)H(4)CH(2)CH(COR(1))(NHCOR(2))(where R(1) = OMe, R(2) = Me; R(1) = OH, R(2) = Me, O(t)Bu). Conversion of the imine to the corresponding amine is achieved by di-acid catalyzed hydroboration. Reaction of ...

Introduction: Both α-amino acids and α-hydroxy acids occur in aqueous extracts of the Murchison carbonaceous meteorite. The Strecker-cyanohydrin reaction, the reaction of carbonyl compounds, cyanide, and ammonia to produce amino and hydroxy acids, has been proposed as a source of such organic acids in meteorites [1]. Such syntheses are consistent with the suggestion [2] that interstellar precur...

The design of folded structures in peptides containing the higher homologues of α-amino acid residues requires the restriction of the range of local conformational choices. In α-amino acids stereochemically constrained residues like α,α-dialkylated residue, aminoisobutyric acid (Aib), and D-Proline ((D)Pro) have proved extremely useful in the design of helices and hairpins in short peptides. Ex...

background: hypothermia is an important complication during surgery, especially in children and is highly associated with serious adverse outcomes. one of the preventive methods is the intraoperative administration of amino acids, which can be effective through increasing thermogenesis and stimulating energy consumption. no studies have been conducted in this regard on children; therefore, we e...