Amino acid similarity matrices are used for protein sequence comparison. It has been shown previously that they can be reconstructed from equivalence classes between amino acids. The goal of the current study is to propose an algorithm for identification of the properties that generate these equivalence classes. An approximate reasoning method for feature extraction and synthesis is developed t...

We analyse sequence and structural features of protein-RNA interfaces using RB-147, a non-redundant dataset of protein-RNA complexes extracted from the PDB. We train classifiers using machine learning algorithms to predict protein-RNA interfaces from sequence and structure-derived features of proteins. Our experiments show that Struct-NB, a Naive Bayes classifier that exploits structural featur...

A selection of bioactive polyphenols different structural classes, such as the ellagitannins vescalagin and vescalin, flavanoids catechin, epicatechin, epigallocatechin gallate (EGCG), procyanidin B2, stilbenoids resveratrol piceatannol, were chemically modified to bear a biotin unit for enabling their immobilization on streptavidin-coated sensor chips. These chips used evaluate in real time by...