نتایج جستجو برای: protein delivery systems

تعداد نتایج: 2509945  

Journal: :Nature Biotechnology 2002

F. Inanlou F. Saraei H. Zolfagharian N. Mohamadpour Dounighi, P. Khaki, S. Moradi Bidhendi

In recent years, encapsulation of drugs and antigens in hydrogels, specifically in calcium alginate particles, is an interesting and practical technique that was developed widespread. It is well known that alginate solution, under proper conditions, can form suitable nanoparticles as a promising carrier system, for vaccine delivery. The aim of this study was to synthesis alginate nanoparticles ...

Induction of protein synthesis by the external delivery of in-vitro transcription-messenger RNA (IVT-mRNA) has been a useful approach in the realm of cell biology, disease treatment, ‎reprogramming of cells, and vaccine design. Therefore, the development of new formulations for ‎protection of mRNA against nucleases is required to maintain its activity in-vivo. It was the aim o...

Induction of protein synthesis by the external delivery of in-vitro transcription-messenger RNA (IVT-mRNA) has been a useful approach in the realm of cell biology, disease treatment, ‎reprogramming of cells, and vaccine design. Therefore, the development of new formulations for ‎protection of mRNA against nucleases is required to maintain its activity in-vivo. It was the aim o...

EXIR MONFARED, I NOURMOHAMMADI, MD FROOZANI,

Protein status of 194 pregnant women and their newborn at a public and a private maternity hospital in Tehran was studied. Blood samples were taken from all women before delivery and from cords at delivery of the placenta. The following determinations were made: total serum protein, protein fractions, creatinine and urea. In the private group, significantly higher maternal mean values were...

Dasatinib is a tyrosine kinase inhibitor (TKI) that is used to treat chronic myeloid leukemiaand in the management of ulcerative colitis (UC) and to provide appropriate results in treatment. Dasatinib is significantly higher and faster than full cytogenetic and large molecular responses as compared to imatinib. In the recent study, using the NMR data, thermochemical properties of the dasa...

Journal: :Biotechnology and bioengineering 2014
Timothy M Martin Beata J Wysocki Jared P Beyersdorf Tadeusz A Wysocki Angela K Pannier

Gene delivery systems transport exogenous genetic information to cells or biological systems with the potential to directly alter endogenous gene expression and behavior with applications in functional genomics, tissue engineering, medical devices, and gene therapy. Nonviral systems offer advantages over viral systems because of their low immunogenicity, inexpensive synthesis, and easy modifica...

Journal: :Journal of Biomaterials and Nanobiotechnology 2011

A common approach for building a drug delivery system is to incorporate the drug within the nanocarrier that results in increased solubility, metabolic stability, and improved circulation time. However, recent developments indicate that selection of polymer nanomaterials can implement more than only inert carrier functions by being biological response modifiers. One representative of such mater...

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